UPF3B Antibodies

Antibodies that detect UPF3B can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. These antibodies target UPF3B in Human, Mouse and Rat samples. Our UPF3B polyclonal antibodies are developed in Rabbit.... Antibodies that detect UPF3B can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. These antibodies target UPF3B in Human, Mouse and Rat samples. Our UPF3B polyclonal antibodies are developed in Rabbit. Find the UPF3B antibody that fits... Antibodies that detect UPF3B can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. These antibodies target UPF3B in Human, Mouse and Rat samples. Our UPF3B polyclonal antibodies are developed in Rabbit. Find the UPF3B antibody that fits your needs. Choose from 1 of 9 UPF3B antibodies, which have been validated in experiments with 3 publications and 33 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for,... Antibodies that detect UPF3B can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. These antibodies target UPF3B in Human, Mouse and Rat samples. Our UPF3B polyclonal antibodies are developed in Rabbit. Find the UPF3B antibody that fits your needs. Choose from 1 of 9 UPF3B antibodies, which have been validated in experiments with 3 publications and 33 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

UPF3B is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The protein is one of two functional homologs to yeast Upf3p. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene.

Synonyms

5730594O13Rik; AI317193; AW541158; HUPF3B; hUpf3p-X; mental retardation, X-linked 62; MRX62; MRXS14; Nonsense mRNA reducing factor 3B; regulator of nonsense transcripts 3B; RENT3B; RGD1560264; Unknown (protein for MGC:134301); UPF3 regulator of nonsense transcripts homolog B; UPF3 regulator of nonsense transcripts homolog B (yeast); UPF3 regulator of nonsense transcripts-like protein B; UPF3B; UPF3B pseudogene 1; UPF3B pseudogene 2; UPF3B pseudogene 3; UPF3B regulator of nonsense mediated mRNA decay; UPF3BP1; UPF3BP2; UPF3BP3; Upf3p-X; UPF3X; up-frameshift suppressor 3 homolog B; Up-frameshift suppressor 3 homolog on chromosome X

UPF3B Antibodies

Target Information

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