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Invitrogen
Complex III Monoclonal Antibody (11A51H12)
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Product Details
43-9400
Product Specifications
Species Reactivity
Bovine,
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
11A51H12
Immunogen
Bovine Heart Complex III
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
HEPES buffered saline
Contains
0.02% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive control: Bovine heart and Human mitochondria
Target Information
Complex III, or ubiquinol cytochrome c oxidoreductase, is a complex of 11 subunits and catalyses electron transfer from reduced ubiquinone or coenzyme Q 10 to cytochrome c. The complex contains 11 different subunits, one of which, cytochrome b, is encoded on mitochondrial DNA, while the remainder subunits are nuclear-encoded. Genetic complex III deficiencies occur but are rare.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Complex III subunit 1; Complex III subunit 10; Complex III subunit 2; Complex III subunit 4; Complex III subunit 5; Complex III subunit 6; Complex III subunit 7; Complex III subunit 8; Complex III subunit 9; Complex III subunit IV; Complex III subunit VII; Complex III subunit VIII; Complex III subunit X; Complex III subunit XI; Core protein I; Core protein II; core protein II precursor; CYC1; Cytochrome b-c1 complex subunit 1, mitochondrial; Cytochrome b-c1 complex subunit 10; Cytochrome b-c1 complex subunit 2, mitochondrial; Cytochrome b-c1 complex subunit 4; Cytochrome b-c1 complex subunit 5; Cytochrome b-c1 complex subunit 6, mitochondrial; Cytochrome b-c1 complex subunit 7; Cytochrome b-c1 complex subunit 8; Cytochrome b-c1 complex subunit 9; Cytochrome b-c1 complex subunit Rieske, mitochondrial; cytochrome bc-1 complex core protein II; Cytochrome c-1; cytochrome c1; Cytochrome c1 non-heme 11 kDa protein; Cytochrome c1 non-heme 7 kDa protein; Cytochrome c1, heme protein, mitochondrial; cytochrome C1, nonheme 7kDa protein; epididymis secretory sperm binding protein; low molecular mass ubiquinone-binding protein (9.5kD); Mitochondrial hinge protein; mitochondrial hinge protein precursor; mitochondrial ubiquinone-binding protein; QP-C; Rieske iron-sulfur protein; Rieske iron-sulfur protein precursor; Rieske protein UQCRFS1; RISP; ubiquinol-cytochrome c reductase (6.4kD) subunit; ubiquinol-cytochrome c reductase complex (7.2 kD); Ubiquinol-cytochrome c reductase complex 11 kDa protein; Ubiquinol-cytochrome c reductase complex 14 kDa protein; Ubiquinol-cytochrome c reductase complex 6.4 kDa protein; Ubiquinol-cytochrome c reductase complex 7.2 kDa protein; Ubiquinol-cytochrome c reductase complex 9.5 kDa protein; Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C; ubiquinol-cytochrome c reductase core protein I; ubiquinol-cytochrome c reductase core protein II; Ubiquinol-cytochrome c reductase iron-sulfur subunit; ubiquinol-cytochrome c reductase, 6.4kDa subunit; ubiquinol-cytochrome c reductase, complex III subunit VI; ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa; ubiquinol-cytochrome c reductase, complex III subunit VIII; ubiquinol-cytochrome c reductase, complex III subunit X, 7.2kDa; Ubiquinol-cytochrome-c reductase complex core protein 1; Ubiquinol-cytochrome-c reductase complex core protein 2; Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit; ubiquinone-binding protein; ubiquinone-binding protein precursor; UCRC; unnamed protein product; UQCRB
Gene Aliases: 0710008D09Rik; CYC1; D3S3191; HSPC051; HSPC119; HSPC151; MC3DN10; MC3DN11; MC3DN3; MC3DN4; MC3DN5; MC3DN6; PKNPY; QCR1; QCR10; QCR2; QCR6; QCR7; QCR8; QCR9; QP-C; QPC; RIP1; RIS1; RISP; UCCR7.2; UCRC; UQBC; UQBP; UQCR; UQCR1; UQCR10; UQCR11; UQCR2; UQCR4; UQCR5; UQCR6; UQCR7; UQCR8; UQCRB; UQCRC1; UQCRC2; UQCRFS1; UQCRH; UQCRQ; UQPC
UniProt ID: (Bovine) P00125, (Human) P08574, (Bovine) P00130, (Human) Q9UDW1, (Human) O14957, (Bovine) P07552, (Bovine) P00129, (Human) P14927, (Bovine) P31800, (Human) B2R7R8, (Bovine) P23004, (Human) P22695, (Bovine) P13272, (Human) P47985, (Bovine) P00126, (Human) P07919, (Human) O14949, (Bovine) P13271
heme binding
metal ion binding
protein binding
ubiquinol-cytochrome-c reductase activity
electron carrier activity
catalytic activity
ubiquitin protein ligase binding
macromolecular complex binding
metalloendopeptidase activity
2 iron, 2 sulfur cluster binding
oxidoreductase activity
iron-sulfur cluster binding
metalloprotease
reductase
oxidoreductase
metabolite interconversion enzyme
mitochondrial electron transport, ubiquinol to cytochrome c
response to glucagon
cellular respiration
hydrogen ion transmembrane transport
generation of precursor metabolites and energy
electron transport chain
oxidative phosphorylation
aerobic respiration
oxidation-reduction process
response to activity
response to alkaloid
proteolysis
respiratory electron transport chain
mitochondrial respiratory chain complex III assembly
subthalamus development
pons development
cerebellar Purkinje cell layer development
hippocampus development
thalamus development
hypothalamus development
pyramidal neuron development
midbrain development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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