Product References
Activation-induced cytidine deaminase expression by thymic B cells promotes T-cell tolerance and limits autoimmunity.
iScience
Lombard-Vadnais F,Chabot-Roy G,Zahn A,Rodriguez Torres S,Di Noia JM,Melichar HJ,Lesage S
Published figure using HELIOS monoclonal antibody (Product # 48-9883-42) in Flow Cytometry
Fri Jan 20 00:00:00 EST 2023
Mesenchymal stem cells transfer mitochondria to allogeneic Tregs in an HLA-dependent manner improving their immunosuppressive activity.
Nature communications
Piekarska K,Urban-Wójciuk Z,Kurkowiak M,Pelikant-Małecka I,Schumacher A,Sakowska J,Spodnik JH,Arcimowicz Ł,Zielińska H,Tymoniuk B,Renkielska A,Siebert J,Słomińska E,Trzonkowski P,Hupp T,Marek-Trzonkowska NM
Published figure using HELIOS monoclonal antibody (Product # 48-9883-42) in Flow Cytometry
Mon Feb 14 00:00:00 EST 2022
Mesenchymal stem cells transfer mitochondria to allogeneic Tregs in an HLA-dependent manner improving their immunosuppressive activity.
Nature communications
Piekarska K,Urban-Wójciuk Z,Kurkowiak M,Pelikant-Małecka I,Schumacher A,Sakowska J,Spodnik JH,Arcimowicz Ł,Zielińska H,Tymoniuk B,Renkielska A,Siebert J,Słomińska E,Trzonkowski P,Hupp T,Marek-Trzonkowska NM
Published figure using HELIOS monoclonal antibody (Product # 48-9883-42) in Flow Cytometry
Mon Feb 14 00:00:00 EST 2022
Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.
Immunity
Harb H,Benamar M,Lai PS,Contini P,Griffith JW,Crestani E,Schmitz-Abe K,Chen Q,Fong J,Marri L,Filaci G,Del Zotto G,Pishesha N,Kolifrath S,Broggi A,Ghosh S,Gelmez MY,Oktelik FB,Cetin EA,Kiykim A,Kose M,Wang Z,Cui Y,Yu XG,Li JZ,Berra L,Stephen-Victor E,Charbonnier LM,Zanoni I,Ploegh H,Deniz G,De Palma R,Chatila TA
Published figure using HELIOS monoclonal antibody (Product # 48-9883-42) in Flow Cytometry
Tue Jun 08 00:00:00 EDT 2021
Potential therapeutic effects of interleukin-35 on the differentiation of naïve T cells into Helios+Foxp3+ Tregs in clinical and experimental acute respiratory distress syndrome.
Molecular immunology
Wang C,Xie K,Li K,Lin S,Xu F
Published figure using HELIOS monoclonal antibody (Product # 48-9883-42) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Adiponectin/AdipoR1 Axis Promotes IL-10 Release by Human Regulatory T Cells.
Frontiers in immunology
Ramos-Ramírez P,Malmhäll C,Tliba O,Rådinger M,Bossios A
Published figure using HELIOS monoclonal antibody (Product # 48-9883-42) in Flow Cytometry
Tue Oct 26 00:00:00 EDT 2021
Immune Dysregulation in Patients With Chromosome 18q Deletions-Searching for Putative Loci for Autoimmunity and Immunodeficiency.
Frontiers in immunology
Hogendorf A,Zieliński M,Constantinou M,Śmigiel R,Wierzba J,Wyka K,Wędrychowicz A,Jakubiuk-Tomaszuk A,Budzynska E,Piotrowicz M,Lipska-Ziętkiewicz BS,Kaczorowska E,Cieślikowska A,Kutkowska-Kaźmierczak A,Fijak-Moskal J,Kugaudo M,Kosińska-Urbańska M,Szadkowska A,Borowiec M,Niedźwiecki M,Trzonkowski P,Młynarski W
48-9883-42 was used in Flow Cytometry to determine the prevalence, mechanism, and genetic background of autoimmunity, immune deficiency, and allergy in a cohort of patients with 18q deletions.
Fri Dec 17 00:00:00 EST 2021
Differences in Maturation Status and Immune Phenotypes of Circulating Helios+ and Helios- Tregs and Their Disrupted Correlations With Monocyte Subsets in Autoantibody-Positive T1D Individuals.
Frontiers in immunology
Zhang Y,Zhang J,Shi Y,Shen M,Lv H,Chen S,Feng Y,Chen H,Xu X,Yang T,Xu K
Published figure using HELIOS monoclonal antibody (Product # 48-9883-42) in Flow Cytometry
Wed Sep 15 00:00:00 EDT 2021
Distinct actions of the fermented beverage kefir on host behaviour, immunity and microbiome gut-brain modules in the mouse.
Microbiome
van de Wouw M,Walsh AM,Crispie F,van Leuven L,Lyte JM,Boehme M,Clarke G,Dinan TG,Cotter PD,Cryan JF
Published figure using HELIOS monoclonal antibody (Product # 48-9883-42) in Flow Cytometry
Mon May 18 00:00:00 EDT 2020
B7-CD28 co-stimulation modulates central tolerance via thymic clonal deletion and Treg generation through distinct mechanisms.
Nature communications
Watanabe M,Lu Y,Breen M,Hodes RJ
48-9883 was used in Flow cytometry/Cell sorting to reveal a function of B7-CD28 co-stimulation in shaping the T cell repertoire and limiting autoimmunity through both thymic clonal deletion and Treg cell generation.
Tue Dec 08 00:00:00 EST 2020
B7-CD28 co-stimulation modulates central tolerance via thymic clonal deletion and Treg generation through distinct mechanisms.
Nature communications
Watanabe M,Lu Y,Breen M,Hodes RJ
48-9883 was used in Flow cytometry/Cell sorting to reveal a function of B7-CD28 co-stimulation in shaping the T cell repertoire and limiting autoimmunity through both thymic clonal deletion and Treg cell generation.
Tue Dec 08 00:00:00 EST 2020
Regulatory T cell features in chronic granulomatous disease.
Clinical and experimental immunology
van de Geer A,Cuadrado E,Slot MC,van Bruggen R,Amsen D,Kuijpers TW
48-9883-42 was used in Flow Cytometry to investigate whether numerical or functional deficiencies exist in Tregs of patients with chronic granulomatous disease.
Thu Aug 01 00:00:00 EDT 2019
Proteomic Analyses of Human Regulatory T Cells Reveal Adaptations in Signaling Pathways that Protect Cellular Identity.
Immunity
Cuadrado E,van den Biggelaar M,de Kivit S,Chen YY,Slot M,Doubal I,Meijer A,van Lier RAW,Borst J,Amsen D
48-9883 was used in Flow cytometry/Cell sorting to suggest that adaptation in signaling pathways protect Treg cell identity and present a resource for further research into Treg cell biology.
Tue May 15 00:00:00 EDT 2018
Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells.
Cell reports
Ogawa C,Bankoti R,Nguyen T,Hassanzadeh-Kiabi N,Nadeau S,Porritt RA,Couse M,Fan X,Dhall D,Eberl G,Ohnmacht C,Martins GA
48-9883-42 was used in Flow Cytometry to study the role of Blimp-1 as a crucial regulator of the Foxp3+RORγt+ regulatory T cell subset.
Tue Oct 02 00:00:00 EDT 2018
Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells.
Nature communications
Downs-Canner S,Berkey S,Delgoffe GM,Edwards RP,Curiel T,Odunsi K,Bartlett DL,Obermajer N
48-9883 was used in Flow cytometry/Cell sorting to demonstrate the tumour-associated conversion of Th17 cells to Treg cells and identify transdifferentiation-associated markers.
Tue Mar 14 00:00:00 EDT 2017
Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells.
The Journal of clinical investigation
Hadland BK,Varnum-Finney B,Poulos MG,Moon RT,Butler JM,Rafii S,Bernstein ID
48-9883 was used in Flow cytometry/Cell sorting to investigate the critical niche components and resident signals required for hematopoietic stem cell induction and self-renewal ex vivo.
Fri May 01 00:00:00 EDT 2015
Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection.
PLoS pathogens
Leeansyah E,Svärd J,Dias J,Buggert M,Nyström J,Quigley MF,Moll M,Sönnerborg A,Nowak P,Sandberg JK
48-9883 was used in Flow cytometry/Cell sorting to show that IL-7 enhances the sensitivity of MAIT cells and induces the arming of effector functions.
Sat Aug 01 00:00:00 EDT 2015