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Abnova
AMIGO3 Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
AMIGO3 Antibody (H00386724-B01P) in WB
Western Blot analysis of AMIGO3 expression in transfected 293T cell line (H00386724-T01) by AMIGO3 MaxPab polyclonal antibody.
Lane 1: AMIGO3 transfected lysate(55.44 KDa).
Lane 2: Non-transfected lysate.
Lane 1: AMIGO3 transfected lysate(55.44 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00386724-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AMIGO3 (NP_942015.1, 1 a.a. approximately 504 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Amount
50 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MTWLVLLGTL LCMLRVGLGT PDSEGFPPRA LHNCPYKCIC AADLLSCTGL GLQDVPAELP AATADLDLSH NALQRLRPGW LAPLFQLRAL HLDHNELDAL GRGVFVNASG LRLLDLSSNT LRALGRHDLD GLGALEKLLL FNNRLVHLDE HAFHGLRALS HLYLGCNELA SFSFDHLHGL SATHLLTLDL SSNRLGHISV PELAALPAFL KNGLYLHNNP LPCDCRLYHL LQRWHQRGLS AVRDFAREYV CLAFKVPASR VRFFQHSRVF ENCSSAPALG LERPEEHLYA LVGRSLRLYC NTSVPAMRIA WVSPQQELLR APGSRDGSIA VLADGSLAIG NVQEQHAGLF VCLATGPRLH HNQTHEYNVS VHFPRPEPEA FNTGFTTLLG CAVGLVLVLL YLFAPPCRCC RRACRCRRWP QTPSPLQELS AQSSVLSTTP PDAPSRKASV HKHVVFLEPG RRGLNGRVQL AVAEEFDLYN PGGLQLKAGS ESASSIGSEG PMTT
Target Information
Amphoterin induced gene and ORF 3 (AMIGO3) is a gene located on chromosome 3p21.31, encoding a member of the AMIGO family of proteins involved in cell adhesion, axon guidance, and neuronal signaling. AMIGO3 is primarily expressed in the central nervous system, playing a crucial role in neural development and the maintenance of neural circuits. Functionally, AMIGO3 contributes to neuronal growth and synapse formation, impacting processes such as neural plasticity and signal transduction. The protein's activity facilitates interactions with other neuronal surface proteins, influencing axon pathfinding and connectivity. Aberrant expression or mutations in AMIGO3 have been linked to neurological disorders and neurodegenerative diseases, suggesting its significance in neural health and pathology. Research into AMIGO3 continues to explore its potential therapeutic applications in promoting neural repair and modulating synaptic functions, offering insights into strategies for addressing nervous system disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alivin-3; AMIGO-3; amphoterin-induced gene and ORF 3; Amphoterin-induced protein 3; MGC120552
Gene Aliases: ALI3; AMIGO-3; AMIGO3; KIAA1851; UNQ6084/PRO20089
UniProt ID: (Human) Q86WK7
Entrez Gene ID: (Human) 386724
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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