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Invitrogen

CD32 Monoclonal Antibody (AT10), PE

1 Reference
View all (38) CD32 antibodies

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Product Details

CD3204

Applications
Tested Dilution
Publications

Flow Cytometry (Flow)

Assay-Dependent
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human

Published species

Hamster

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

AT10

Immunogen

Human CD32

Conjugate

PE PE PE

Excitation/Emission Max

565/576 nm View spectra spectra

Form

Liquid

Purification

purified

Storage buffer

PBS with BSA, sucrose

Contains

0.1% sodium azide

Storage conditions

4°C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10376008

Product Specific Information

R-phycoerythrin (PE) is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing an exceptional quantum yields and molar extinction coefficients.

Target Information

This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.

Analyte Specific Reagent

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Bioinformatics

Protein Aliases: CD32; CD32 receptor 2; CD32 receptor 2a; CDw32; Fc fragment of IgG receptor IIa; Fc fragment of IgG receptor IIb; Fc fragment of IgG receptor IIc; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc fragment of IgG, low affinity IIc, receptor for (CD32); Fc gamma receptor IIC; Fc gamma receptor RIIa3; Fc gamma RIIb; Fc-gamma RII-a; Fc-gamma RII-b; Fc-gamma RII-c; Fc-gamma-RIIa; Fc-gamma-RIIb; Fc-gamma-RIIc; FCGR2B; FcgRIIa3 splice variant; fcRII-a; fcRII-b; FGFR2B; IgG Fc fragment receptor; IgG Fc fragment receptor precursor; IgG Fc receptor alpha-Fc-gamma-RII; IgG Fc receptor beta-Fc-gamma-RII; IgG Fc receptor II-a; IgG Fc receptor II-b; IgG Fc receptor II-c; IgG Fc receptor precursor; Immunoglobulin G Fc receptor II; immunoglobulin G Fc receptor II-c; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; MGC23887; MGC30032; RP11-5K23.6; unnamed protein product

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Gene Aliases: CD32; CD32A; CD32B; CD32C; CDW32; FCG2; FcgammaRIIa; FcgammaRIIb; FcgammaRIIc; FcGR; FCGR2; FCGR2A; FCGR2A1; FCGR2B; FCGR2C; FcGRIIB; FcRII-c; FCRIIC; IGFR2

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UniProt ID: (Human) P12318, (Human) P31994, (Human) P31995

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Entrez Gene ID: (Human) 2212, (Human) 2213, (Human) 9103

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Function(s)
protein binding IgG receptor activity IgG binding beta-amyloid binding low-affinity IgG receptor activity macromolecular complex binding transmembrane signaling receptor activity
Process(es)
antibody-dependent cellular cytotoxicity regulation of immune system process immune response cell surface receptor signaling pathway positive regulation of tumor necrosis factor production Fc-gamma receptor signaling pathway positive regulation of phagocytosis negative regulation of type I hypersensitivity negative regulation of antibody-dependent cellular cytotoxicity negative regulation of cytokine production immune effector process follicular dendritic cell activation mature B cell differentiation involved in immune response follicular B cell differentiation immune complex clearance by monocytes and macrophages negative regulation of dendritic cell antigen processing and presentation regulation of B cell antigen processing and presentation negative regulation of immunoglobulin production regulation of adaptive immune response negative regulation of acute inflammatory response to antigenic stimulus positive regulation of humoral immune response negative regulation of humoral immune response mediated by circulating immunoglobulin receptor-mediated endocytosis phagocytosis phagocytosis, engulfment defense response inflammatory response response to bacterium immunoglobulin mediated immune response antigen processing and presentation of exogenous peptide antigen via MHC class II cerebellum development negative regulation of B cell proliferation negative regulation of interleukin-10 production negative regulation of macrophage activation negative regulation of cytotoxic T cell degranulation regulation of innate immune response mast cell activation positive regulation of JNK cascade negative regulation of phagocytosis negative regulation of immune response negative regulation of B cell receptor signaling pathway negative regulation of B cell activation cellular response to molecule of bacterial origin regulation of immune complex clearance by monocytes and macrophages negative regulation of neutrophil activation regulation of dendritic spine maintenance regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway cellular response to beta-amyloid positive regulation of response to endoplasmic reticulum stress negative regulation of dendritic cell differentiation immune system process
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