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Proteintech
CD155/PVR Monoclonal Antibody (SKII.4), CoraLite® Plus 594
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FIGURE: 1 / 1
CD155/PVR Antibody (CL594-65251) in Flow
U-937 cells (positive) and Jurkat cells (negative) were mixed 1:1 and 1x10^6 cells were surface stained with 5 µL CoraLite Plus 594 Anti-Human CD155/PVR (CL594-65251, Clone: SKII.4) (red) or CoraLite594 Mouse IgG1 Isotype Control (CL594-65124, Clone: MOPC-21) (blue). Cells were not fixed.
Product Details
CL594-65251
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
SKII.4
Immunogen
SK-N-AS human neuroblastoma cells
Conjugate
Excitation/Emission Max
588/604 nm
Form
Liquid
Concentration
5 µL/Test
Purification
Affinity chromatography
Storage buffer
PBS with 0.5% BSA
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Wet ice
Target Information
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD155; FLJ25946; NECL-5; nectin-like 5; Nectin-like protein 5; Poliovirus receptor; sCD112; soluble CD112; unnamed protein product
Gene Aliases: CD155; HVED; Necl-5; NECL5; PVR; PVS; TAGE4
UniProt ID: (Human) P15151
Entrez Gene ID: (Human) 5817
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
signal transduction
natural killer cell mediated cytotoxicity
susceptibility to natural killer cell mediated cytotoxicity
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
viral entry into host cell
susceptibility to T cell mediated cytotoxicity
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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