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CD26 Recombinant Mouse Monoclonal Antibody (BA5b), CoraLite® Plus 594
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FIGURE: 1 / 2
CD26 Antibody (CL594-65574) in Flow
1x10^6 human PBMCs were surface stained with APC Anti-Human CD3 and 5 µL CoraLite® Plus 594 Anti-Human CD26 (BA5b) Mouse IgG2a Recombinant Antibody (CL594-65574, Clone: BA5b) or CoraLite®594 Mouse IgG2a Isotype Control (C1.18.4) (CL594-65208, Clone: C1.18.4). Cells were not fixed.
Product Details
CL594-65574
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
BA5b
Immunogen
A human T cell clone
Conjugate
Excitation/Emission Max
588/604 nm
Form
Liquid
Concentration
5 µL/Test
Purification
Protein A
Storage buffer
PBS with 0.5% BSA
Contains
0.09% sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Wet ice
Target Information
CD26 (dipeptidyl peptidase IV, DPP IV), adenosine deaminase (ADA) binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family. CD26 is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. CD26 identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. Further, CD26 is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Alterations in CD26 peptidase activity are characteristic of malignant transformation, and the enzymatic activity increases dramatically with tumor grade and severity. CD26 is expressed in various blood cell types, but also in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADABP; ADCP-2; Adenosine deaminase complexing protein 2; CD26; Dipeptidyl peptidase 4; Dipeptidyl peptidase IV; dipeptidylpeptidase 4; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); DPP IV; DPP-IV; Gly-Pro naphthylamidase; Post-proline dipeptidyl aminopeptidase IV; T-cell activation antigen CD26; TP103; Xaa-Pro-dipeptidylaminopeptidase
Gene Aliases: ADABP; ADCP2; CD26; DPP4; DPPIV; TP103
UniProt ID: (Human) P27487
Entrez Gene ID: (Human) 1803
virus receptor activity
protease binding
aminopeptidase activity
serine-type endopeptidase activity
receptor binding
protein binding
peptidase activity
serine-type peptidase activity
dipeptidyl-peptidase activity
hydrolase activity
identical protein binding
protein homodimerization activity
chemorepellent activity
behavioral fear response
response to hypoxia
proteolysis
cell adhesion
positive regulation of cell proliferation
negative regulation of extracellular matrix disassembly
peptide hormone processing
receptor-mediated endocytosis of virus by host cell
T cell costimulation
regulation of cell-cell adhesion mediated by integrin
locomotory exploration behavior
psychomotor behavior
T cell activation
endothelial cell migration
viral entry into host cell
receptor-mediated virion attachment to host cell
negative chemotaxis
membrane fusion
negative regulation of neutrophil chemotaxis
glucagon processing
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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