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HIP55 Polyclonal Antibody
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FIGURE: 1 / 1
HIP55 Antibody (BS-20165R) in WB
Lane 1: mouse lymph lysates; Lane 2: mouse spleen lysates probed with HIP55 Polyclonal Antibody, Unconjugated (bs-20165R) at 1:300 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37°C.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
BS-20165R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human HIP55, amino acids 201-300.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin-binding protein 1; adaptor protein; cervical mucin-associated protein; cervical SH3P7; drebrin F; drebrin-F; HIP-55; HPK1-interacting protein of 55 kDa; SH3 domain-containing protein 7; src homology 3 domain-containing protein HIP-55; unnamed protein product
Gene Aliases: ABP1; HIP-55; HIP55; mAbp1; SH3P7
UniProt ID: (Human) Q9UJU6, (Mouse) Q62418
Entrez Gene ID: (Human) 28988, (Mouse) 13169
endocytosis
synapse assembly
Rac protein signal transduction
neuron projection morphogenesis
membrane organization
podosome assembly
postsynaptic actin cytoskeleton organization
regulation of actin filament polymerization
positive regulation of axon extension
positive regulation of dendritic spine morphogenesis
Disclaimer
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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