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Proteintech
IMPDH2 Polyclonal Antibody
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Product Details
12948-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IMPDH2 Fusion Protein Ag3632 (1-350 aa encoded by BC012840)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Amount
39 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MADYLISGG TSYVPDDGLT AQQLFNCGDG LTYNDFLILP GYIDFTADQV DLTSALTKKI TLKTPLVSSP MDTVTEAGMA IAMALTGGIG FIHHNCTPEF QANEVRKVKK YEQGFITDPV VLSPKDRVRD VFEAKARHGF CGIPITDTGR MGSRLVGIIS SRDIDFLKEE EHDCFLEEIM TKREDLVVAP AGITLKEANE ILQRSKKGKL PIVNEDDELV AIIARTDLKK NRDYPLASKD AKKQLLCGAA IGTHEDDKYR LDLLAQAGVD VVVLDSSQGN SIFQINMIKY IKDKYPNLQV IGGNVVTAAQ AKNLIDAGVD ALRVGMGSGS ICITQEVLAC GRPQATAVYK V (1-350 aa encoded by BC012840)
Target Information
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein; IMP (inosine 5'-monophosphate) dehydrogenase 2; IMP (inosine monophosphate) dehydrogenase 2; IMP dehydrogenase 2; IMP dehydrogenase 2 {ECO:0000255|HAMAP-Rule:MF_03156}; IMP dehydrogenase II; IMP dehydrogenase type II; IMP oxireductase 2; IMPD 2; IMPD 2 {ECO:0000255|HAMAP-Rule:MF_03156}; IMPDH 2; IMPDH 2 {ECO:0000255|HAMAP-Rule:MF_03156}; IMPDH II; IMPDH-II; inosine 5' phosphate dehydrogenase 2; inosine 5'-phosphate dehydrogenase 2; inosine 5-monophosphate dehydrogenase 2; inosine monophosphate dehydrogenase 2; inosine monophosphate dehydrogenase type II; inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205); Inosine-5'-monophosphate dehydrogenase 2; inosine-5'-monophosphate dehydrogenase 2 {ECO:0000255|HAMAP-Rule:MF_03156}; Inosine-5'-monophosphate dehydrogenase type II; unnamed protein product
Gene Aliases: IMPD; IMPD 2; IMPD2; IMPDH 2; IMPDH-II; IMPDH2
UniProt ID: (Human) P12268, (Rat) E9PU28, (Mouse) P24547
Entrez Gene ID: (Human) 3615, (Rat) 301005, (Mouse) 23918
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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