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Invitrogen
JLP Polyclonal Antibody
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FIGURE: 1 / 1
JLP Antibody (PA5-75646) in WB
Western blot analysis of JLP in Lane 1: AML-12 whole cell lysate (40 µg), Lane 2: U-87MG whole cell lysate (40 µg), Lane 3: EC9706 whole cell lysate (40 µg), Lane 4: SGC7901 whole cell lysate (40 µg). Samples were incubated with JLP polyclonal antibody (Product # PA5-75646) at a dilution of 1:500.
Product Details
PA5-75646
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues in Human JLP.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-Jun N-terminal kinase protein-associated leucine-zipper protein; c-Jun NH2-terminal kinase-associated leucine zipper protein; C-Jun-amino-terminal kinase-interacting protein 4; Cancer/testis antigen 89; CT89; HLC-6; Human lung cancer oncogene 6 protein; JIP-4; JLP; JNK interacting protein; JNK-associated leucine-zipper protein; JNK-interacting leucine zipper; JNK-interacting protein 4; JNK/SAPK-associated protein; JNK/SAPK-associated protein 2; JSAP2; lung cancer oncogene 4; lung cancer oncogene 6; Max-binding protein; Mitogen-activated protein kinase 8-interacting protein 4; PHET; PIG6; proliferation-inducing gene 6; Proliferation-inducing protein 6; Protein highly expressed in testis; Sperm surface protein; Sperm-associated antigen 9; Sperm-specific protein; Sunday driver 1; unnamed protein product
Gene Aliases: 3110018C07Rik; 4733401I23Rik; 4831406C20Rik; AW552012; CT89; HLC-6; HLC4; HLC6; HSS; JIP-4; JIP4; JLP; JSAP2; JSAP2a; KIAA0516; MAPK8IP4; PHET; PIG6; SPAG9; SYD1
UniProt ID: (Human) O60271, (Mouse) Q58A65
Entrez Gene ID: (Human) 9043, (Rat) 360600, (Mouse) 70834
MAPK cascade
vesicle-mediated transport
positive regulation of cell migration
lysosome localization
retrograde transport, endosome to Golgi
positive regulation of MAPK cascade
negative regulation of neuron differentiation
positive regulation of neuron differentiation
striated muscle cell differentiation
negative regulation of dendrite extension
activation of MAPK activity
activation of JUN kinase activity
biological_process
protein homooligomerization
negative regulation of protein homodimerization activity
positive regulation of signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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