Immunogen sequence: EAYGRLDLDTD SADGLSAPLL ASPEPSAGPL QVAAPAHSHA GGPGPTEH
Highest antigen sequence identity to the following orthologs - mouse 86%, rat 88%.
This gene is located in the surfeit gene cluster, a group of very tightly linked housekeeping genes that do not share sequence similarity. The gene is oriented in a head-to-head fashion with RPL7A (SURF3) and the two genes share a bidirectional promoter. The encoded proteins are localized to the cytoplasm. Two alternative transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Mediator complex subunit 22; Mediator of RNA polymerase II transcription subunit 22; MGC48682; Surf-5; Surfeit locus protein 5
Gene Aliases: MED22; MED24; surf-5; SURF5
UniProt ID: (Human) Q15528
Entrez Gene ID: (Human) 6837