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This gene is located in the surfeit gene cluster, a group of very tightly linked housekeeping genes that do not share sequence similarity. The gene is oriented in a head-to-head fashion with RPL7A (SURF3) and the two genes share a bidirectional promoter. The encoded proteins are localized to the cytoplasm. Two alternative transcript variants encoding different isoforms have been identified for this gene.
AW212655; AW558812; MED22; MED24; Mediator complex subunit 22; mediator of RNA polymerase II transcription subunit 22; MGC48682; RGD1564893; si:ch73-278c20.1; si:dkey-226m8.2; surf5; Surf-5; surfeit 5; surfeit 5 isoform b; surfeit gene 5; surfeit locus protein 5; wu:fj45h07; zgc:86721
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