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Immunogen sequence: MAQQRALPQS KETLLQSYNK RLKDDIKSIM DNFTEIIKTA KIEDETQVSR ATQGEQDNYE MHVRAANIVR AGESLMKLVS DLKQFLILND FPSVNEAIDQ RNQQLRTLQE ECDRKLITLR DEISIDLYEL EEEYYSSRYK; Positive Samples: U-87MG, A-431, A-549, Mouse testis; Cellular Location: Nucleus
This gene is located in the surfeit gene cluster, a group of very tightly linked housekeeping genes that do not share sequence similarity. The gene is oriented in a head-to-head fashion with RPL7A (SURF3) and the two genes share a bidirectional promoter. The encoded proteins are localized to the cytoplasm. Two alternative transcript variants encoding different isoforms have been identified for this gene.
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Protein Aliases: Mediator complex subunit 22; Mediator of RNA polymerase II transcription subunit 22; MGC48682; Surf-5; surfeit 5; surfeit gene 5; Surfeit locus protein 5
Gene Aliases: AW212655; AW558812; MED22; MED24; RGD1564893; Surf-5; SURF5
UniProt ID: (Human) Q15528, (Rat) A0JPN6, (Mouse) Q62276
Entrez Gene ID: (Human) 6837, (Rat) 499762, (Mouse) 20933
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