Hamburger Menu Button
Thermo Fisher Scientific Logo
Se connecter
Vous n’avez pas de compte? Créer votre compte
  • Produits
    • Anticorps
    • Oligos, amorces, sondes et gènes
    • Réactions PCR en temps réel Taqman
    • Milieux de culture cellulaire
    • Produits chimiques
    • Colonnes et cartouches de chromatographie
    • Équipement de laboratoire
    • Consommables en plastique et fournitures de laboratoire
    • Microplaques
    • Produits plus écologiques
    • Afficher toutes les catégories de produits
  • Applications
    • Bioprocédés
    • Culture cellulaire et transfection
    • Thérapie cellulaire et génétique
    • Chromatographie
    • Tests moléculaires
    • Solutions numériques
    • Extraction et analyse d’ADN et d’ARN
    • Spectroscopie, analyse élémentaire et isotopique
    • Voir toutes les applications et techniques
  • Services
    • Services CDMO et CRO à 360°
    • Services CDMO
    • Services CRO
    • Services personnalisés
    • Services financiers et leasing
    • Services pour les instruments
    • Informatique de laboratoire
    • Offres commerciales et OEM
    • Services de formation
    • Unity Lab Services
    • Voir tous les services
  • Aide et assistance
    • S’inscrire et créer un compte
    • Comment commander
    • Assistance instruments
    • Centres d’assistance technique
    • Centres d’apprentissage
    • Consultez toutes les rubriques d'aide et d'assistance
  • Populaire
    • TaqMan Real-Time PCR Assays
      Reaction PCR en temps réel TaqMan
    • Antibodies
      Anticorps
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt - Synthèse Gène
    • Cell Culture Plastics
      Plastiques culture cellulaire
  • Nos clients
    • Biotechnologie
    • Industrie biopharmaceutique
    • CDMO
    • Diagnostics de laboratoire
    • Sciences industrielles et appliquées associées
  • Promotions
  • Contactez-nous
  • Commande rapide
  • Suivi et statut de la commande
  • Documents et certificats
Thermo Fisher Scientific Logo

Search

Rechercher
Search button
          • Statut des commandes
          • Commande rapide
          • Promos
          • Se connecter
            Se connecter
            Vous n’avez pas de compte? Créer votre compte
            • Mon compte
            • Commandes
            • Connect: lab, données, apps
            • Produits personnalisés et projets
            • Services Central
          • Primary Antibodies ›
          • MECP2 Antibodies

          Fabgennix

          MeCP2 isoform 1 Polyclonal Antibody

          View all (46) MECP2 antibodies

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support

          Cite MeCP2 isoform 1 Polyclonal Antibody

          Additional Information:
          {{banner.description}}
          {{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
          • Antibody Testing Data (1)
          MeCP2 isoform 1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          MeCP2 isoform 1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

          {{ $ctrl.currentElement.advancedVerification.fullName }}
          {{ $ctrl.currentElement.advancedVerification.text }}

          MeCP2 isoform 1 Antibody (MECP2E1-112AP) in WB

          Western blot of MR1 (MR1-101AP) with C2C12 cells. Apparent MW is 45 kDa. 1:250 dilution in DilObufferTM (FGI-1963). Project # 5004B Panel B2 Lane 7 Lot # MR1. 3166 PB2.AP. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

          {{$ctrl.videoDesc}}

          {{$ctrl.videoLongDesc}}

          MeCP2 isoform 1 Antibody in Western Blot (WB)
          MeCP2 isoform 1 Polyclonal Antibody

          Product Details

          MECP2E1-112AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          ELISA (ELISA)

          1:10,000
          -

          Immunoprecipitation (IP)

          1:50-1:250
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide taken within amino acid region 1-50 on mouse Methyl-CpG-binding Protein 2 isoform 1 protein.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5-1.5 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain. MECP2 is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. MECP2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: DKFZp686A24160; MeCp-2 protein; MECP2A; methyl CpG binding protein 2 (Rett syndrome) isoform MECP2_1; methyl CpG binding protein 2 (Rett syndrome) isoform MECP2_2; methyl CpG binding protein 2 (Rett syndrome) isoform MECP2_3; methyl CpG binding protein 2 (Rett syndrome) isoform MECP2_5; methyl CpG binding protein 2 (Rett syndrome) isoform MECP2_6; methyl CpG binding protein 2 (Rett syndrome) isoform MECP2_7; methyl CpG binding protein 2 (Rett syndrome) isoform MECP2_8; Methyl-CpG-binding protein 2; Rett Syndrome transcript 1; Rett syndrome; MECP2B; transcript variant; transcriptional repressor; involved in Rett syndrome disease; unnamed protein product

          View more View less

          Gene Aliases: 1500041B07Rik; AUTSX3; D630021H01Rik; Mbd5; MECP2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; WBP10

          View more View less

          UniProt ID: (Human) P51608, (Mouse) Q9Z2D6

          View more View less

          Entrez Gene ID: (Human) 4204, (Mouse) 17257

          View more View less

          Function(s)
          nucleic acid binding DNA binding chromatin binding transcription corepressor activity RNA binding mRNA binding protein binding methyl-CpG binding double-stranded methylated DNA binding siRNA binding binding, bridging histone reader activity molecular condensate scaffold activity promoter-specific chromatin binding four-way junction DNA binding transcription factor activity, sequence-specific DNA binding transcription factor binding enzyme binding protein domain specific binding chromatin DNA binding histone deacetylase binding poly(A) RNA binding unmethylated CpG binding protein N-terminus binding DNA metabolism protein
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter behavioral fear response response to hypoxia startle response neurological system process involved in regulation of systemic arterial blood pressure regulation of respiratory gaseous exchange by neurological system process inositol metabolic process regulation of transcription from RNA polymerase II promoter glutamine metabolic process cellular biogenic amine metabolic process Notch signaling pathway chemical synaptic transmission synapse assembly brain development respiratory gaseous exchange learning memory long-term memory protein localization glucocorticoid metabolic process cell proliferation associative learning adult locomotory behavior visual learning post-embryonic development gene expression regulation of gene expression negative regulation of gene expression glial cell proliferation dendrite development negative regulation of angiogenesis proprioception sensory perception of pain cerebellum development ventricular system development neuron differentiation neuron projection development heterochromatin assembly cardiolipin metabolic process multicellular organismal response to stress social behavior regulation of gene expression, epigenetic neuron maturation negative regulation of neuron apoptotic process negative regulation of blood vessel endothelial cell migration hypermethylation of CpG island negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter phosphatidylcholine metabolic process regulation of synaptic plasticity cell development catecholamine secretion neuromuscular process controlling posture neuromuscular process negative regulation of developmental process negative regulation of smooth muscle cell differentiation response to other organism excitatory postsynaptic potential positive regulation of glial cell proliferation long-term synaptic potentiation genetic imprinting positive regulation of microtubule nucleation trans-synaptic signaling by BDNF regulation of multicellular organismal development mitochondrial electron transport, ubiquinol to cytochrome c chromatin silencing regulation of gene expression by genetic imprinting transcription, DNA-templated regulation of transcription, DNA-templated positive regulation of cell proliferation pathogenesis embryo development histone methylation histone acetylation negative regulation of histone methylation negative regulation of histone acetylation regulation of DNA methylation negative regulation of astrocyte differentiation positive regulation of synapse assembly
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          Commander Plus Icon Minus Icon
          • Statut des commandes
          • Assistance commandes
          • Commande rapide
          • Centre d’approvisionnement
          • Approvisionnement en ligne
          Assistance Plus Icon Minus Icon
          • Aide et assistance
          • Contactez-nous
          • Centres d’assistance technique
          • Documents et certificats
          • Signaler un problème sur le site
          Ressources Plus Icon Minus Icon
          • Centres d’apprentissage
          • Promotions
          • Événements et séminaires en ligne
          • Réseaux sociaux
          À propos de Thermo Fisher Plus Icon Minus Icon
          • À propos de nous À propos de nous
          • Emplois Emplois
          • Investisseurs Investisseurs
          • Actualités Actualités
          • Responsabilité sociale Responsabilité sociale
          • Marques commerciales
          • Politiques et notices d’information
          Notre portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Unity Lab Services
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Information Center
          • Price & Freight Policy
          © 2006-2026 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          France flag icon
          France

          Your items have has been added!


          Host server : magellan-search-green-7d94cb4b65-mrft7:80/100.66.76.145:80.
          git-commit: c9e08c96761173abe34e68f880379696776a4827
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.44.1-2026.02.97.1.0