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|Tested species reactivity||Human, Mouse, Rabbit, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the C-terminal region of PDE4A (common to all PDE4A proteins).|
|Purification||Antigen affinity chromatography|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-31131 detects PDE4A from human, mouse, rabbit, rat samples.
PA1-31131 has been successfully used in immunocytochemistry, immunofluorescence, immunoprecipitation, Western blot applications.
The PA1-31131 immunogen is a synthetic peptide corresponding to the C-terminal region of PDE4A (common to all PDE4A proteins).
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4A is a class IV cAMP-specific PDE (summary by Milatovich et al., 1994 [PubMed 8009369]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cAMP-specific 3',5'-cyclic phosphodiesterase 4A; cAMP-specific phosphodiesterase PDE4A; cyclic AMP specific phosphodiesterase PDE4A5A; cyclic AMP-specific phosphodiesterase OCPDE4A1A; DPDE2; dunce; PDE4; phosphodiesterase 4A, cAMP specific; phosphodiesterase 4A, cAMP-specific; phosphodiesterase 4A, cAMP-specific (dunce; phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila); phosphodiesterase E2 dunce homolog, Drosophila; phosphodiesterase isozyme 4
D9Ertd60e; DPDE2; PDE4; PDE46; PDE4A; PHOSA