Dynamis Medium and ActiCHO P Medium had equivalent titer growth at day 14, in fed-batch culture, but Dynamis Medium had additional titer growth at day 18
An IgG-producing CHO-DG44 external cell line was cultured in Dynamis Medium and EfficientFeed C+ Supplement and other commercially available media and feeds for a period of up to 18 days. Titer values normalized to 100% to the best competitor on Day 18.
AchtiCHO could not sustain culture viability to the 18-day time point. Balance CD CHO was close to Dynamis Medium in titer growth, but required 3 times more the feeding volume.