| Year |
Reprogrammed cell type |
Reference |
Species |
| 2018 |
PBMC |
Han L, et al (2018) Characterization of Hematopoietic Differentiation Profiles of MPN Patient-Derived Inducible Pluripotent Stem Cells Harboring Homozygous Vs Heterozygous Calreticulin Mutations Blood Dec. 1, 2018 132:3065; doi.org/10.1182/blood-2018-99-113372 |
Human |
| 2018 |
Fibroblast |
Bariana TK, et al (2018) Sphingolipid dysregulation due to lack of functional KDSR impairs proplatelet formation causing thrombocytopenia Haematologica Nov 22 2018: haematol.2018.204784 Doi:10.3324/haematol.2018.204784 |
Human |
| 2018 |
PBMC |
Calado SM, et al (2018) Generation of a human iPS cell line from a patient with retinitis pigmentosa due to EYS mutation Stem Cell Res Nov. 16, 2018, 33: 251-254 doi.org/10.1016/j.scr.2018.11.002 |
Human |
| 2018 |
Fibroblast |
Sanjurjo-Soriano C, et al (2018) Generation of a human iPSC line, INMi002-A, carrying the most prevalent USH2A variant associated with Usher syndrome type 2 Stem Cell Res Nov. 16, 2018, 33: 247-250 doi.org/10.2016/j.scr.2018.11.007 |
Human |
| 2018 |
Fibroblast |
Sanjurjo-Soriano C, et al (2018) Generation of an iPSC line, INMi001-A, carrying the two most common USH2A mutations from a compound heterozygote with non-syndromic retinitis pigmentosa Stem Cell Res Nov. 10, 2018, 33: 228-232 doi.org/10.1016/j.scr.2018.11.004 |
Human |
| 2018 |
Uterine cells |
Gartz M, et al (2018) Exosomes exert cardioprotection in dystrophin-deficient cardiomyocytes via ERK1/2-p38/MAPK signaling Scientific Reports Nov. 8, 2018 8: 16519 DOI:10.1038/s41598-018-34879-6 |
Human |
| 2018 |
Fibroblast |
Xue Y, et al (2018) Synthetic mRNAs Drive Highly Efficient iPS Cell Differentiation to Dopaminergic Neurons STEM CELLS TRANSLATIONAL MEDICINE Nov 1, 2018, 1-12 |
Human |
| 2018 |
Fibroblast |
Smith J, et al (2018) Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits Stem Cell Reports Nov. 1, 2018 11:1-14 doi.org/10.1016/j.stemcr.2018.10.006 |
Human |
| 2018 |
PBMC |
Ciampi O, et al (2018) Generation of two isogenic iPS cell lines (IRFMNi002-A and IRFMNi002-B) from a patient affected by Focal Segmental Glomerulosclerosis carrying a heterozygous c.565G > A mutation in PAX2 gene Stem Cell Res Oct 29, 2018 22:175-179 doi.org/10.1016/j.scr.2018.10.018 |
Human |
| 2018 |
PBMC |
Ye H, et al (2018) Efficient Generation of Non-Integration and Feeder-Free Induced Pluripotent Stem Cells from Human Peripheral Blood Cells by Sendai Virus Cell Physiol Biochem Oct 14, 2018;50:1318–1331, doi.org/10.1159/000494589 |
Human |
| 2018 |
Fibroblast |
Kutsche LK, et al (2018) Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis Cell Systems October 24, 2018, pp 438-452, doi.org/10.1016/j.cels.2018.08.011 |
Human |
| 2018 |
Fibroblast |
Monzio C, et al (2018) Mitochondrial Dysregulation and Impaired Autophagy in iPSC-Derived Dopaminergic Neurons of Multiple System Atrophy, Stem Cell Reports Oct 18, 2018, 11: 1-14, doi.org/10.1016/j.stemcr.2018.09.007 |
Human |
| 2018 |
Fibroblast |
Machuca C, et al (2018) Generation of human induced pluripotent stem cell (iPSC) line from an unaffected female carrier of mutation in SACSIN gene Stem Cell Res Oct 12, 2018 33: 166-170 doi.org/10.1016/j.scr.2018.10.016 |
Human |
| 2018 |
Fibroblast |
Fuet A, et al (2018) NANOG Is Required for the Long-Term Establishment of Avian Somatic Reprogrammed Cells Stem Cell Res Oct 11, 2018 doi.org/10.1016/j.stemcr.2018.09.005 |
Chicken |
| 2018 |
MSC |
Kim S, et al (2018) Exosomes Secreted from Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Accelerate Skin Cell Proliferation Int. J. Mol. Sc. Oct 11, 2018, 19:3119 |
Human |
| 2018 |
Uterine-derived cells |
Cao Y, et al (2018) Generation of a Urine-Derived Ips Cell Line from a Patient with a Ventricular Septal Defect and Heart Failure and the Robust Differentiation of These Cells to Cardiomyocytes via Small Molecules Cell Physiol Biochem Oct 11, 2018 50:538-551 DOI: 10.1159/00049416 |
Human |
| 2018 |
Fibroblasts |
Lukovic D, et al (2018) Generation of a human iPSC line from a patient with Leber congenital amaurosis caused by mutation in AIPL1 Stem Cell Res; Oct 6, 2018 33: 151-155 doi.org/10.1016/j.scr.2018.10.012 |
Human |
| 2018 |
Fibroblasts |
Pellegrini S, et al (2018) Differentiation of Sendai virus-reprogrammed iPSC into β cells, compared with human pancreatic islets and immortalized β cell line Cell Transplantation 2018; Sept 29; pp 1-13; doi: 10.1177/0963689718798564 |
Human |
| 2018 |
Fibroblasts |
Ahmed E, et al (2018) Generation of the induced pluripotent stem cell line UHOMi001-A from a patient with mutations in CCDC40 gene causing Primary Ciliary Dyskinesia (PCD) Stem Cell Res 2018, Sept 28, 33: 15-19 doi.org/10.1016/j.scr.2018.09.019 |
Human |
| 2018 |
Fibroblasts |
Bianchi F, et al (2018) Rapid and efficient differentiation of functional motor neurons from human iPSC for neural injury modelling Stem Cell Res 2018; Sept 26, 32: 126-134 doi.org/10.1016/j.scr.2018.09.006 |
Human |
| 2018 |
PBMC |
Chan YH, et al (2018) Generation of induced pluripotent stem cells from a patient with hearing loss carrying GJB2 p.V37I mutation Stem Cell Res 2018, Oct 3, 33: 51-55, doi.org/10.1016/j.scr.2018.10.002 |
Human |
| 2018 |
Skin biopsies |
Buchrieser J, et al (2018) RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation Cell Death & Disease 2018 Sept 24; 9:973; doi 10.1038/s41419-018-1053-4 |
Human |
| 2018 |
PBMC |
Brookhouser N, et al (2018) Generation and characterization of two human induced pluripotent stem cell (hiPSC) lines homozygous for the Apolipoprotein e4 (APOE4) risk variant—Alzheimer's disease (ASUi005-A) and healthy non-demented control (ASUi006-A) Stem Cell Res 2018; Sept 21; doi.org/10.10.1016/j.scr.2018.09.007 |
Human |
| 2018 |
Fibroblast |
Volpato V, et al (2018) Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study Stem Cell Res 2018; Sept 20; doi.org/10.1016/j.stemcr.2018.08.013 |
Human |
| 2018 |
Fibroblast |
Chang KH, et al (2018) Modeling Alzheimer’s Disease by Induced Pluripotent Stem Cells Carrying APP D678H Mutation Molecular Neurobiology 2018; Sept 20; doi.org/10.1007s.12035-018-1336-x |
Human |
| 2018 |
PBMC |
Gomez Limia CE, et al (2018) Characterization of a human induced Pluripotent Stem (iPS) cell line (INCABRi002-A) derived from a primary myelofibrosis patient harboring the 5-bp insertion in CALR and the p.W146X mutation in TP53 Stem Cell Res 2018; Sept 20; doi.org/10.1016/j.scr.2018.09.12 |
Human |
| 2018 |
Fibroblast |
Yu M, et al (2018) Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease OJRD 2018; Sept 18; Orphanet Journal of Rare Diseases 201813:152; doi.org/10.1186/s13023-018-0886-3 |
Human |
| 2018 |
Fibroblast |
Palladino VS, et al (2018) Generation of human induced pluripotent stem cell lines (hiPSC) from one bipolar disorder patient carrier of a DGKH risk aplotype and one non-risk-variant-carrier bipolar disorder patient Stem Cell Res (2018); Sept 17; doi.org/10.2016/j.scr.2018.09.008 |
Human |
| 2018 |
CD34+ |
Toofan P, et al (2018) Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal protein Cell Death & Disease 2018, Sept 11; Cell Death & Disease 9, Article number: 927 (2018) |
Human |
| 2018 |
PBMC |
Ali M, et al (2018) Comparative transcriptome analysis of hESC- and iPSC-derived corneal endothelial cells ScienceDirect 2018, Sept 6; doi.org/10.1016/j.exer.2018.08.023 |
Human |
| 2018 |
Fibroblasts |
Seibler P, et al (2018) Iron overload is accompanied by mitochondrial and lysosomal dysfunction in WDR45 mutant cells Brain 2018 Aug 30. doi: 10.1093/brain/awy230 |
Human |
| 2018 |
Fibroblasts |
Yuan S, et al (2018) Tauopathy-associated PERK alleles are functional hypomorphs that increase neuronal vulnerability to ER stress Human Molecular Genetics August 29, 2018; doi.org/10.1093/hmg/ddy297 |
Human |
| 2018 |
Fibroblasts |
Shanmughapriya S, et al (2018) FOXD1-dependent MICU1 expression regulates mitochondrial activity and cell differentiation Nature Communications (9, article number: 3449) 2018, August 29; |
Human |
| 2018 |
Heptocyte-like cell (HLC) |
Kiamehr M, et al (2018) hiPSC-derived hepatocytes closely mimic the lipid profile of primary hepatocytes: A future personalised cell model for studying the lipid metabolism of the liver J Cell Physiol. 2018 Aug 26. doi: 10.1002/jcp.27131. |
Human |
| 2018 |
PBMC |
Potirat P, et al (2018) Establishment of a human iPSC line (MUsIi007-A) from peripheral blood of normal individual using Sendai viral vectors Stem Cell Res 2018; August 17; doi.org/10.1016/j.scr.2018.08.014 |
Human |
| 2018 |
CD34+ cells |
Barnes J, et al (2018) Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells Molecular Autism August 15, 2018; 9:44; doi.org/10.1186/s13229-018-0227-3 |
Human |
| 2018 |
Arterial endothelial cells |
Li H, et al (2018) Integration-free reprogramming of human umbilical arterial endothelial cells into induced pluripotent stem cells IHSTMi001-A Stem Cell Res 2018; August 12; doi.org/10.1016/j.scr.2018.08.007 |
Human |
| 2018 |
Fibroblasts |
Nakai R, et al (2018) Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata) Scientific Reports August 15, 2018; 8: 12187; DOI:10.1038/s41598-018-30734-w |
Monkey (Macaca fuscata) |
| 2018 |
Neurons |
Rakovic A, et al (2018) Genome editing in induced pluripotent stem cells rescues TAF1 levels in X-linked dystonia-parkinsonism Mov Disord. 2018 Jul; 33(7):1108-1118. doi: 10.1002/mds.27441. |
Human |
| 2018 |
Fibroblasts |
Xiong Y, et al (2018) Induction of pluripotent stem cells by reprogramming human ocular fibroblasts under xeno-free conditions Arq Bras Oftalmol. 2018;81(5):376-83 |
Human |
| 2018 |
CD34+ from cord blood |
Duan F, et al (2018) Biphasic modulation of insulin signaling enables highly efficient hematopoietic differentiation from human pluripotent stem cells Stem Cell Research & Therapy 2018, July 27 9:205 doi.org/10.1186/s13287-018-0934-x |
Human |
| 2018 |
Fibroblasts |
Arellano CM, et al (2018) Generation of a human iPSC line from a patient with autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) caused by mutation in SACSIN gene Stem Cell Res 2018; July 27; doi.org/10.1016/j.scr.2018.07.012 |
Human |
| 2018 |
Epidermal Keratinocytes |
Devito L, et al (2018) Induced pluripotent stem cell line from an atopic dermatitis patient heterozygous for c.2282del4 mutation in filaggrin: KCLi001-A Stem Cell Res 2018; July 25; 31:12-126; doi.org/10.2016/j.scr.2018.07.014 |
Human |
| 2018 |
PBMC |
Kuramoto Y, et al 2018 Generation of Fabry cardiomyopathy model for drug screening using induced pluripotent stem cell-derived cardiomyocytes from a female Fabry patient J Molecular and Cellular Cardiology 2018; August; 121:256-265; doi.org/10.1016/j.yjmcc.2018.07.246 |
Human |
| 2018 |
Cells |
Ntai A, et al (2018) Trehalose to cryopreserve human pluripotent stem cells Stem Cell Res 2018; July 25; doi.org/10.1016/j.scr.2018.07.021 |
Human |
| 2018 |
PBMC |
Kasai-Brunswick TH, et al (2018) Generation of patient-specific induced pluripotent stem cell lines from one patient with Jervell and Lange-Nielsen syndrome, one with type 1 long QT syndrome and two healthy relatives Stem Cell Res 2018; July 25; doi.org/10.1016/j.scr.2018.07.016 |
Human |
| 2018 |
Fibroblasts |
Swaroop M, et al (2018) Patient iPSC-derived neural stem cells exhibit phenotypes in concordance with the clinical severity of Mucopolysaccharidosis I Human Molecular Genetics 2018; July 19; doi.org/10.1093/hmg/ddy259 |
Human |
| 2018 |
Keratinocytes |
Boonkaew B, et al (2018) Induced pluripotent stem cell line MUSIi006-A derived from hair follicle keratinocytes as a non-invasive somatic cell source Stem Cell Res 2018 Jul 18;31:79-82. doi: 10.1016/j.scr.2018.07.007. [Epub ahead of print] |
Human |
| 2018 |
Human oral mucosal epithelial cells |
Trevisan M, et al (2018) Oral Mucosa-Derived Induced Pluripotent Stem Cells from Patients with Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome Cell Reprogram 2018 Jul 10. doi: 10.1089/cell.2017.0064. [Epub ahead of print] |
Human |
| 2018 |
Fibroblasts |
Pietraszek-Gremplewicz K, et al. 2018 Heme Oxygenase-1 Influences Satellite Cells and Progression of Duchenne Muscular Dystrophy in Mice ARS 2018; July 10, 29: Issue 2; doi.org/10.1089/ars.2017.7435 |
Human |
| 2018 |
Fibroblasts |
Rizzuti M, et al. (2018) MicroRNA expression analysis identifies a subset of downregulated miRNAs in ALS motor neuron progenitors Scientific Reports 2018; July 04; 8:10105; DOI:10.1038/s41598-018-28366-1 |
Human |
| 2018 |
Adipose tissue-derived MSCs |
Choi HY, et al. (2018) Generation of a human induced pluripotent stem cell line KSCBi003-A, from human adipose tissue-derived mesenchymal stem cells using a chromosomal integration-free system Stem Cell Res. 2018 Jun 27;31:1-4. doi: 10.1016/j.scr.2018.06.003. [Epub ahead of print] |
Human |
| 2018 |
Fibroblasts |
Little D, et al. (2018) A Single cell high content assay detects mitochondrial dysfunction in iPSC-derived neurons with mutations in SNCA Scientific Reports 2018; June 13; 8:9033 DOI:10.1038/s41598-018-27058-0 |
Human |
| 2018 |
PBMCs |
Alari V, et al. (2018) Generation of the Rubinstein-Taybi syndrome type 2 patient-derived induced pluripotent stem cell line (IAli001-A) carrying the EP300 exon 23 stop mutation c.3829A>T, p.(Lys1277*) Stem Cell Res. 2018; June 11; 30:175-179; doi.org/10.1016/j.scr.2018.06.009 |
Human |
| 2018 |
PBMC |
Benedetti V, et al (2018) Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery EBioMedicine 2018; June 06; 16 pages. doi.org/10.1016/j.ebiom.2018.06.005 |
Human |
| 2018 |
PBMC |
Alari V, et al. (2018) iPSC-derived neurons of CREBBP- and EP300 mutated Rubinstein-Taybi syndrome patients show morphological alterations and hypoexcitability Stem Cell Res. 2018; May 30; 30: 130-140; doi.org/10.1016/j.scr.2018.05.019 |
Human |
| 2018 |
Fibroblasts |
Richard E, et al. (2018) Generation and characterization of two human iPSC lines from patients with methylmalonic acidemia cblB type Stem Cell Res.2018 May;29:143-147. doi: 10.1016/j.scr.2018.03.021. Epub 2018 Apr 5. |
Humans |
| 2018 |
Urine cells |
Guo Y, et al. (2018) Generation of an iPS cell line via a non-integrative method using urine-derived cells from a patient with USH2A-associated retinitis pigmentosa Stem Cell Res. 2018 May;29:139-142. doi: 10.1016/j.scr.2018.03.022. Epub 2018 Apr 6. |
Human |
| 2018 |
Fibroblast |
Torriano S, et al. (2018) The effect of PTC124 on choroideremia fibroblasts and iPSC-derived RPE raises considerations for therapy Scientific Reports 2018; May 29; 8: 8234 DOI:10.1038/s41598-018-26481-7 |
Human |
| 2018 |
PBMC |
Peitz M, et al. (2018) Blood-derived integration-free iPS cell line UKBi011-A from a diagnosed male Alzheimer’s disease patient with APOE ɛ4/ ɛ4 genotype Stem Cell Res. 2018; May; 29: 250-253; doi.org/10.1016/j.scr.2018.04.011 |
Human |
| 2018 |
Fibroblast |
Je G, et al. (2018) A novel extended form of alpha-synuclein 3’UTR in the human brain Molecular Brain 2018; May 25; 11:29; doi.org/10.1186/s13041-018-0371-x |
Human |
| 2018 |
Cells |
Ou J, et al. (2018) iPSCs from a Hibernator Provide a platform for Studying Cold Adaptation and Its Potential Medical Applications Cell Press 2018; May 3; 173: 851-863; doi.org/10.1016/j.cell.2018.03.010 |
Human, Ground-squirrel |
| 2018 |
PBMC |
Park S, et al. (2018) Generation of Human Induced Pluripotent Stem Cells using a defined, Feeder-Free Reprogramming System Current Protocols in Stem Cell Biology 2018; May 04; doi.org/10.1002/cpsc.48 |
Human |
| 2018 |
Urinary cells |
Zhang J, et al. (2018) Generation of a human induced pluripotent stem cell line from urinary cells of a patient with primary congenital glaucoma using integration free Sendai technology Stem Cell Res. 2018; May; 29:162-165. doi10.1016/j.scr.2018.04.004. Epub 2018 Apr 9. |
Human |
| 2018 |
PBMC |
Hsu CC, et al. (2018) Generation of induced pluripotent stem cells from a patient with Best Dystrophy carrying 11q12.3 (BEST1 (VMD2)) mutation Stem Cell Res. 2018; May; 29:134-138. doi.org/10.1016/j.scr.2018.03.019 |
Human |
| 2018 |
Fibroblasts, DPSC |
Pisal R. (2018) Cellular Reprogramming as a Tool for Harvesting Patient Specific Stem Cells Dissertation Thesis, May 2018 dsspace.cuni.cz |
Human |
| 2018 |
PBMC |
Sharma A, et al. (2018) Human Induced Pluripotent Stem Cell Production and Expansion from Blood using a Non-Integrating Viral Reprogramming Vector Current Protocols in Molecular Biology 2018, April; 58:1-14; doi: 10.1002/cpmb.58 |
Human |
| 2018 |
Fibroblasts |
Kim HW, et al (2018) Differential effects on sodium current impairments by distinct SCN1A mutations in GABAergic neurons derived from Dravet syndrome patients Brain Dev 2018 Apr;40(4):287-298. doi: 10.1016/j.braindev.2017.12.002. Epub 2017 Dec 30. |
Human |
| 2018 |
Fibroblasts |
Eisen B, et al. (2018) Generation of Duchenne muscular dystrophy patient-specific induced pluripotent stem cell line lacking exons 45-50 dystrophin gene (IITi001-A) Stem Cell Res. 2018; April; 29:111-114; DOI: 10.1016/j.scr.2018.03.023 |
Human |
| 2018 |
Exfoliated renal epithelial cells (RE) |
Pars S, et al (2018) Generation and characterization of a human iPS cell line from a patient related control to study disease mechanisms associated with DAND5 p.R152H alteration Stem Cell Res. 2018; April 28; 29:202-206; doi.org/10.1016/j.scr.2018.04.015 |
Human |
| 2018 |
PBMC |
Lu HE, et al (2018) Generation of patient-specific induced pluripotent stem cells from Leber's hereditary optic neuropathy Stem Cell Res 2018 Apr;28:56-60. doi: 10.1016/j.scr.2018.01.029. Epub 2018 Jan 31 |
Human |
| 2018 |
PBMC |
Liu SP, et al (2018) Generation of novel induced pluripotent stem cell (iPSC) line from a 16-year-old sialidosis patient with NEU-1 gene mutation Stem Cell Res 2018 Apr;28:39-43. doi: 10.1016/j.scr.2018.01.024. Epub 2018 Jan 31. |
Human |
| 2018 |
PBMC |
Fernandez-Susavila H, et al (2018) Generation and characterization of the human iPSC line IDISi001-A isolated from blood cells of a CADASIL patient carrying a NOTCH3 mutation Stem Cell Res 2018 Apr;28:16-20. doi: 10.1016/j.scr.2018.01.023. Epub 2018 Jan 31. |
Human |
| 2018 |
Fibroblast |
Sima N, et al. (2018) Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses OJRD 2018; 13:54;April 10; doi.org/10.1186/s13023-018-0798-2 |
Human |
| 2018 |
Fibroblasts |
Jansch C, et al (2018) Generation of a human induced pluripotent stem cell (iPSC) line from a 51-year-old female with attention-deficit/hyperactivity disorder (ADHD) carrying a duplication of SLC2A3 Stem Cell Res 2018 Apr;28:136-140. doi: 10.1016/j.scr.2018.02.005. Epub 2018 Feb 13. |
Human |
| 2018 |
Fibroblasts |
Bolinches-Amoros A, et al (2018) Generation of a human iPSC line from a patient with congenital glaucoma caused by mutation in CYP1B1 gene. Stem Cell Res. 2018 Apr;28:96-99. doi: 10.1016/j.scr.2018.01.004. Epub 2018 Jan 4. |
Human |
| 2018 |
Urine cells |
Wang Y, et al (2018) Generation of induced pluripotent stem cell line (ZZUi004-A) from urine sample of a patient with spinocerebellar ataxia type 3 Stem Cell Res 2018 Apr;28:71-74. doi: 10.1016/j.scr.2018.01.027. Epub 2018 Jan 31. |
Human |
| 2018 |
Fibroblasts |
Marote A, et al (2018) Generation of an induced pluripotent stem cell line (CSC-41) from a Parkinson's disease patient carrying a p.G2019S mutation in the LRRK2 gene Stem cell Res 2018; April; 28:44-77;DOI: 10.1016/j.scr.2018.01.022 |
Human |
| 2018 |
PBMC |
Yuhuan X, et (2018) Generation of GZKHQi001-A and GZWWTi001-A, two induced pluripotent stem cell lines derived from peripheral blood mononuclear cells of Duchenne muscular dystrophy patients Stem Cell Res 2018 Apr;28:25-28. doi: 10.1016/j.scr.2018.01.028. Epub 2018 Jan 31. |
Human |
| 2018 |
Fibroblasts |
Zhan Y, et al. (2018) Establishment of a PRKAG2 cardiac syndrome disease model and mechanism study using human induced pluripotent stem cells J Mol Cell Cardiol 2018 Apr;117:49-61. doi: 10.1016/j.yjmcc.2018.02.007. Epub 2018 Feb 13. |
Human |
| 2018 |
PBMC |
Wu S, et (2018) Induced Pluripotent Stem Cells Promote Retinal Ganglion Cell Survival After Transplant IOVS 2018; March, 2018; 59:1571-1576; doi:10.1167/iovs.17-23648 |
Human |
| 2018 |
PBMC |
Eckford PDW, et al. (2018) The CF Canada-Sick Kids Program in individual CF therapy: A resource for the advancement of personalized medicine in CF JCF 2018; March 31; JCF-01643; doi.org/10.1016/j.jcf.2018.03.013 |
Human |
| 2018 |
Fibroblasts |
Battrawy IE, et al. (2018) Modeling Short QT Syndrome Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes J Am Heart Assoc. 2018; March 24; 7:e0077394; doi.org/10.1161/JAHA.117.0077394 |
Human |
| 2018 |
cells |
Sato C, et al. (2018) Tau Kinetics in Neurons and the Human Central Nervous System Neuron 2018; March 21; 97:1284-1298; doi.org/10.1016/j.neuron.2018.02.015 |
Human |
| 2018 |
Fetus |
Ferrer CM, et al. (2018) An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality Genes & Dev. 2018; March 19; 1-3; doi: 10.1101/gad.307330.117 |
Human |
| 2018 |
N/A |
Ulmer BM, et al (2018) Contractile Work Contributes to Maturation of Energy Metabolism in hiPSC-Derived Cardiomyocytes Stem Cell Reports 2018 Mar 13;10(3):834-847. doi: 10.1016/j.stemcr.2018.01.039. Epub 2018 Mar 1. |
Human |
| 2018 |
Urine cells |
San H, et al (2018) Generation of induced pluripotent stem cell line (ZZUi011-A) from urine sample of a normal human Stem Cell Res. 2018; March 09; 29:28-31; doi.org/10.1016/j.scr.2018.03.002 |
Human |
| 2018 |
PBMC |
Griscelli F, et al (2018) Generation of a human induced pluripotent stem cell line (VRFi001-A) from orbital adipose tissue of a bilateral retinoblastoma patient with heterozygous RB1 gene deletion Stem Cell Res 2018; March 07; 29:42-45; doi.org/10.1016/j.scr.2018.03.012 |
Human |
| 2018 |
Fibroblasts |
Wu YT, et al (2018) Generation of an induced pluripotent stem cell (iPSC) line from a 40-year-old patient with the A8344G mutation of mitochondrial DNA and MERRF (myoclonic epilepsy with ragged red fibers) syndrome Stem Cell Res 2018 Mar;27:10-14. doi: 10.1016/j.scr.2017.12.013. Epub 2017 Dec 19. |
Human |
| 2018 |
PBMC |
Navara CS, et al. (2018) Optimization of culture conditions for the derivation and propagation of baboon (Papio anubis) induced pluripotent stem cells PLoS One 2018 Mar 1;13(3):e0193195. doi: 10.1371/journal.pone.0193195. eCollection 2018 |
Baboon |
| 2018 |
Fibroblasts |
Wattanapanitch M, et al (2018) Generation of a human induced pluripotent stem cell line (MUSIi001-A) from caesarean section scar fibroblasts using Sendai viral vectors Stem Cell Res 2018 Mar;27:105-108. doi: 10.1016/j.scr.2018.01.013. Epub 2018 Jan 9. |
Human |
| 2018 |
Fibroblasts |
Marote A. et al (2018) Generation of an induced pluripotent stem cell line (CSC-44) from a Parkinson's disease patient carrying a compound heterozygous mutation (c.823C>T and EX6 del) in the PARK2 gene Stem Cell Res. 2018 Mar;27:90-94. doi:10.1016/j.scr.2018.01.006. Epub 2018 Jan 4. |
Human |
| 2018 |
Fibroblasts |
Marote A, et al (2018) Generation of an integration-free induced pluripotent stem cell line (CSC-43) from a patient with sporadic Parkinson's disease. Stem Cell Res. 2018 Mar;27:82-85. doi: 10.1016/j.scr.2018.01.007. Epub 2018 Jan 4. |
Human |
| 2018 |
Fibroblasts |
Savchenko E, et al (2018) Generation of a human induced pluripotent stem cell line (CSC-42) from a patient with sporadic form of Parkinson's disease Stem Cell Res. 2018 Mar;27:78-81. doi: 10.1016/j.scr.2018.01.002. Epub 2018 Jan 4. |
Human |
| 2018 |
Fibroblasts |
Russ K, et al. (2018) Generation of a human induced pluripotent stem cell line (CSC-40) from a Parkinson's disease patient with a PINK1 p.Q456X mutation Stem Cell Res. 2018 Mar;27:61-64. doi: 10.1016/j.scr.2018.01.001. Epub 2018 Jan 4. |
Human |
| 2018 |
PBMC |
Luo Y, et. (2018) Generation of an induced pluripotent stem cell line from an adult male with 45,X/46,XY mosaicism Stem Cell Res 2018 Mar;27:42-45. doi: 10.1016/j.scr.2018.01.003. Epub 2018 Jan 5. |
Human |
| 2018 |
Fibroblasts |
Iannielli A, et al. (2018) Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson's Disease Models Cell Rep 2018 Feb 20;22(8):2066-2079. doi: 10.1016/j.celrep.2018.01.089. |
Human |
| 2018 |
Fibroblasts |
Kreienkamp R, et (2018) A Cell-Intrinsic Interferon-like Response Links Replication Stress to Cellular Aging Caused by Progerin Cell Rep 2018 Feb 20;22(8):2006-2015. doi: 10.1016/j.celrep.2018.01.090. |
Human |
| 2018 |
Fibroblasts |
Kroeger H, et al (2018) The unfolded protein response regulator ATF6 promotes mesodermal differentiation Sci.Signal.2018 Feb 13;11(517). pii: eaan5785. doi: 10.1126/scisignal.aan5785. |
Human |
| 2018 |
Fibroblasts |
Sahakyan V, et al (2018) Folic Acid Exposure Rescues Spina Bifida Aperta Phenotypes in Human Induced Pluripotent Stem Cell Model Sci. Rep 2018 Feb 13;8(1):2942. doi: 10.1038/s41598-018-21103-8. |
Human |
| 2018 |
CD34+ cells |
Ye L, et al. (1018) MiR-126 enhances VEGF expression in induced pluripotent stem cell-derived retinal neural stem cells by targeting spred-1 Int J Clin Exp Pathol 2018; Feb 01; 11(2):1023-1030. |
Human |
| 2018 |
PBMC |
Long C, et (2018) Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing Sci Adv 2018 Jan 31;4(1):eaap9004. doi: 10.1126/sciadv.aap9004. eCollection 2018 Jan. |
Human |
| 2018 |
Fibroblasts |
Russell OM, et al (2018) Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo Scientific Reports 2018; Jan 29; 8:1799 DOI:10.1038/s41598-018-20064-2. |
Human |
| 2018 |
Fibroblasts |
Romano G, et al. (2018) Downregulation of glutamic acid decarboxylase in Drosophila TDP-43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses. Sci Rep. 2018 Jan 29;8(1):1809. doi: 10.1038/s41598-018-19802-3. |
Human |
| 2018 |
EBV immortalized lymphoblastoids |
Martineau L, et al (2018) Lymphoblastoids cell lines - Derived iPSC line from a 26-year-old myotonic dystrophy type 1 patient carrying (CTG)200 expansion in the DMPK gene: CHUQi001-A Stem Cell Res 2018 Jan;26:103-106. doi: 10.1016/j.scr.2017.12.010. Epub 2017 Dec 16. |
Human |
| 2018 |
Fibroblasts |
Kucherenko MM, et (2018) Stress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival Nat Commun 2018 Jan 22;9(1):312. doi: 10.1038/s41467-017-02757-w. |
Human |
| 2018 |
Keratinocytes/Hair |
Sulkowski M, et (2018) Introduction of Exogenous HSV-TK Suicide Gene Increases Safety of Keratinocyte-Derived Induced Pluripotent Stem Cells by Providing Genetic "Emergency Exit" Switch Int J Mol Sci 2018 Jan 9;19(1). pii: E197. doi: 10.3390/ijms19010197. |
Human |
| 2018 |
Fibroblasts |
Kim S, et al. (2018) GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers PNAS 2018; Jan 08;DOI:10.1073/pnas.1700465115. |
Human |
| 2017 |
Fibroblasts |
Rodriguez-Madoz, JR et al (2017) Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome PLoS One 2017 Dec 27;12(12):e0190275. doi: 10.1371/journal.pone.0190275. eCollection 2017. |
Human |
| 2017 |
Fibroblasts |
He J, et (2018) Generation of Induced Pluripotent Stem Cells from Patients with COL3A1 Mutations and Differentiation to Smooth Muscle Cells for ECM-Surfaceome Analyses Methods Mol Biol 2018;1722:261-302. doi: 10.1007/978-1-4939-7553-2_17. |
Human |
| 2017 |
Fibroblasts |
Hoffman GE, et al (2017) Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains Nat. Commun 2017 Dec 20;8(1):2225. doi: 10.1038/s41467-017-02330-5. |
Human |
| 2017 |
Fibroblasts |
Walsh P, et al (2017) Defined Culture Conditions Accelerate Small-molecule-assisted Neural Induction for the Production of Neural Progenitors from Human-induced Pluripotent Stem Cells Cell Transplant 2017 Dec;26(12):1890-1902. doi: 10.1177/0963689717737074. |
Human |
| 2017 |
Dental mesenchymal stem cells (SCAP, DPSCs) |
Tan X, et al. (2017) Efficient generation of transgene- and feeder-free induced pluripotent stem cells from human dental mesenchymal stem cells and their chemically defined differentiation into cardiomyocytes Biochem Biophys Res Comm. In press 05 Dec 17. |
Human |
| 2017 |
Dermal fibroblasts |
Parrotta E, et al. (2017) Two sides of the same coin? Unraveling subtle differences between human embryonic and induced pluripotent stem cells by Raman spectroscopy Stem Cell Research & Therapy 2017 8:271 https://doi.org/10.1186/s13287-017-0720-1. |
Human |
| 2017 |
Peripheral blood |
Rybová J, et al. (2017) Neural cells generated from human induced pluripotent stem cells as a model of CNS involvement in mucopolysaccharidosis type II J Inherit Metab Dis. 2017 Nov 22. doi: 10.1007/s10545-017-0108-5. |
Human |
| 2017 |
Dermal fibroblasts and T-cells |
Oksanen M, et al. (2017) PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease Stem Cell Reports. 2017 Dec 12;9(6):1885-1897. doi: 10.1016/j.stemcr.2017.10.016. |
Human |
| 2017 |
Fibroblasts |
You YR, et al. (2017) Generation of induced pluripotent stem cell (iPSC) line from a 21-year-old X-linked adrenoleukodystrophy (X-ALD) patient Stem Cell Res. 2017 Dec;25:136-138. doi: 10.1016/j.scr.2017.10.016. |
Human |
| 2017 |
PBMCs |
Hsu YH, et al. (2017) Generation of an induced pluripotent stem cell line from a 39-year-old female patient with severe-to-profound non-syndromic sensorineural hearing loss and a A1555G mutation in the mitochondrial MTRNR1 gene Stem Cell Res. 2017 Dec;25:245-249. doi: 10.1016/j.scr.2017.10.024. |
Human |
| 2017 |
PBMCs |
Xu T, et al. (2017) Generation of integration-free induced pluripotent stem cell line (NJMUi001-A) from a phenylketonuria patient Stem Cell Res. 2017 Dec;25:179-182. doi: 10.1016/j.scr.2017.11.008. |
Human |
| 2017 |
Dermal fibroblasts |
Wang Y, et al. (2017) Generation of induced pluripotent stem cell line (ZZUi005-A) from a 21-year-old patient with a novel RAB39B gene mutation in X-linked juvenile parkinsonism Stem Cell Res. 2017 Dec;25:132-135. doi: 10.1016/j.scr.2017.10.021. |
Human |
| 2017 |
Dermal fibroblasts |
Wang Z, et al. (2017) Establishment of induced pluripotent stem cell line (ZZUi010-A) from an Alzheimer's disease patient carrying an APP gene mutation Stem Cell Res. 2017 Dec;25:213-216. doi: 10.1016/j.scr.2017.10.025. |
Human |
| 2017 |
PBMCs |
Lin CH, et al. (2017) Generation of induced pluripotent stem cells from a patient with Parkinson's disease carrying LRRK2 p.I2012T mutation Stem Cell Res. 2017 Dec;25:123-127. doi: 10.1016/j.scr.2017.10.020. |
Human |
| 2017 |
PBMCs |
Lee JJ, et al. (2017) Induced pluripotent stem cells derived from an autosomal dominant polycystic kidney disease patient carrying a PKD1 Q533X mutation Stem Cell Res. 2017 Dec;25:83-87. doi: 10.1016/j.scr.2017.10.026. |
Human |
| 2017 |
Urine epithelial cells |
Cristo F, et al. (2017) Generation of human iPSC line from a patient with laterality defects and associated congenital heart anomalies carrying a DAND5 missense alteration Stem Cell Res. 2017 Dec;25:152-156. doi: 10.1016/j.scr.2017.10.019. |
Human |
| 2017 |
PBMCs |
Fujimori K, et al. (2017) Escape from Pluripotency via Inhibition of TGF-β/BMP and Activation of Wnt Signaling Accelerates Differentiation and Aging in hPSC Progeny Cells Stem Cell Reports. 2017 Nov 14;9(5):1675-1691. doi: 10.1016/j.stemcr.2017.09.024. |
Human |
| 2017 |
Dermal fibroblasts |
Fu S, et al. (2017) Generation of human-induced pluripotent stem cells from burn patient-derived skin fibroblasts using a non-integrative method Int J Mol Med. 2018 Jan;41(1):87-94. doi: 10.3892/ijmm.2017.3206. |
Human |
| 2017 |
Dermal fibroblasts |
Son D, et al. (2017) Generation of two induced pluripotent stem cell (iPSC) lines from X-linked adrenoleukodystrophy (X-ALD) patients with adrenomyeloneuropathy (AMN) Stem Cell Res. 2017 Dec;25:46-49. doi: 10.1016/j.scr.2017.10.003. |
Human |
| 2017 |
Hair follicle keratinocytes |
Adhya D, et al. (2017) Understanding role of steroids in typical and atypical brain development: Advantages of using a “brain in a dish” approach J Neuroendocrinol. 2017 Oct 12. doi: 10.1111/jne.12547. [Epub ahead of print] |
Human |
| 2017 |
PBMCs |
Ho MC, et al. (2017) Generation of an induced pluripotent stem cell line, IBMS-iPSC-014-05, from a female autosomal dominant polycystic kidney disease patient carrying a common mutation of R803X in PKD2 Stem Cell Res. 2017 Dec;25:38-41. doi: 10.1016/j.scr.2017.10.005. |
Human |
| 2017 |
Dermal fibroblasts |
Duncan G, et al. (2017) Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Stem Cells Dev. 2017 Dec 1;26(23):1695-1705. doi: 10.1089/scd.2017.0172. |
Human |
| 2017 |
Dermal fibroblasts |
Terray A, et al. (2017) Establishment of an induced pluripotent stem (iPS) cell line from dermal fibroblasts of an asymptomatic patient with dominant PRPF31 mutation Stem Cell Res. 2017 Dec;25:26-29. doi: 10.1016/j.scr.2017.10.007. |
Human |
| 2017 |
Dermal fibroblasts |
Russo FB, et al. (2017) Modeling the Interplay Between Neurons and Astrocytes in Autism Using Human Induced Pluripotent Stem Cells Biol Psychiatry. 2017 Oct 3. pii: S0006-3223(17)32009-7. doi: 10.1016/j.biopsych.2017.09.021. |
Human |
| 2017 |
Dermal fibroblasts |
Romero-Moya D, et al. (2017) Generation, genome edition and characterization of iPSC lines from a patient with coenzyme Q10 deficiency harboring a heterozygous mutation in COQ4 gene Stem Cell Res. 2017 Oct;24:144-147. doi: 10.1016/j.scr.2016.09.007. Epub 2016 Sep 16. |
Human |
| 2017 |
PBMCs |
Huang CY, et al. (2017) Generation of induced pluripotent stem cells derived from an autosomal dominant polycystic kidney disease patient with a p.Ser1457fs mutation in PKD1 Stem Cell Res. 2017 Oct;24:139-143. doi: 10.1016/j.scr.2017.09.004. |
Human |
| 2017 |
PBMCs |
Griscelli F, et al. (2017) Generation of induced pluripotent stem cell (iPSC) line from a patient with triple negative breast cancer with hereditary exon 17 deletion of BRCA1 gene Stem Cell Res. In press 14 Sep 17. |
Human |
| 2017 |
Dermal fibroblasts |
Wu J, et al. (2017) Generation of an induced pluripotent stem cell line (CSCRMi001-A) from a patient with a new type of limb-girdle muscular dystrophy (LGMD) due to a missense mutation in POGLUT1 (Rumi) Stem Cell Res. 2017 Oct; 24:102-105 https://doi.org/10.1016/j.scr.2017.08.020. |
Human |
| 2017 |
Amniotic fluid cells |
Yan J, et al. (2017) Generation of Induced Pluripotent Stem Cells from Amniotic Fluid Cells of a Fetus with Hb Bart's Disease Hemoglobin 2017 Published online 24 Aug 2017 http://dx.doi.org/10.1080/03630269.2017.1353523. |
Human |
| 2017 |
Fibroblasts |
Zurita-Diaz F, et al. (2017) Establishment of a human DOA'plus' iPSC line, IISHDOi003-A, with the mutation in the OPA1 gene: c. 1635C> A; p. Ser545Arg Stem Cell Res. 2017 Oct; 24:81-84 https://doi.org/10.1016/j.scr.2017.08.017. |
Human |
| 2017 |
Dermal fibroblasts |
Weir G, et al. (2017) Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source Brain, awx201 https://doi.org/10.1093/brain/awx201. |
Human |
| 2017 |
Adipose tissue-derived mesenchymal multipotent stromal cells |
Khudiakov A, et al. (2017) Generation of iPSC line from desmin-related cardiomyopathy patient carrying splice site mutation of DES gene Stem Cell Res. 2017 Oct; 24:77-80 https://doi.org/10.1016/j.scr.2017.08.015. |
Human |
| 2017 |
Adipose tissue-derived mesenchymal multipotent stromal cells |
Khudiakov A, et al. (2017) Generation of iPSC line from patient with arrhythmogenic right ventricular cardiomyopathy carrying mutations in PKP2 gene Stem Cell Res. 2017 Oct; 24:84-88 https://doi.org/10.1016/j.scr.2017.08.014. |
Human |
| 2017 |
PBMCs |
Mora C, et al. (2017) Generation of induced pluripotent stem cells (iPSC) from an atrial fibrillation patient carrying a KCNA5 p. D322H mutation Stem Cell Res. 2017 Oct; 24:29-32 https://doi.org/10.1016/j.scr.2017.08.009. |
Human |
| 2017 |
PBMCs |
Mora C, et al. (2017) Generation of induced pluripotent stem cells (iPSC) from an atrial fibrillation patient carrying a PITX2 p. M200V mutation Stem Cell Res. 2017 Oct; 24:8-11 https://doi.org/10.1016/j.scr.2017.08.007. |
Human |
| 2017 |
CD34+ cells |
Limia CEG, et al. (2017) Generation and characterization of a human induced pluripotent stem (iPS) cell line derived from an acute myeloid leukemia patient evolving from primary myelofibrosis carrying the CALR 52 bp deletion and the ASXL1 p.R693X mutation Stem Cell Res. 2017 Oct; 24:16-20 https://doi.org/10.1016/j.scr.2017.08.006. |
Human |
| 2017 |
Dermal fibroblasts |
Terray A, et al. (2017) Generation of an induced pluripotent stem cell (iPSC) line from a patient with autosomal dominant retinitis pigmentosa due to a mutation in the NR2E3 gene Stem Cell Res. 2017 Oct; 24:1-4 https://doi.org/10.1016/j.scr.2017.08.003. |
Human |
| 2017 |
Fibroblasts |
Ortuño-Costela M (2017) Establishment of a human iPSC line (IISHDOi001-A) from a patient with McArdle disease Stem Cell Res. 2017 Aug;23:188-192. doi: 10.1016/j.scr.2017.07.020. Epub 2017 Jul 28. |
Human |
| 2017 |
PBMCs |
Griscelli F, et al. (2017) Generation of an induced pluripotent stem cell (iPSC) line from a patient with maturity-onset diabetes of the young type 13 (MODY13) with a the potassium inwardly-rectifying channel, subfamily J, member 11 (KCNJ11) mutation. Stem Cell Res. 2017 Aug;23:178-181. doi: 10.1016/j.scr.2017.07.023. Epub 2017 Jul 25. |
Human |
| 2017 |
PBMCs |
Bennaceur-Griscelli A, et al. (2017) Generation of an induced pluripotent stem cell line from a patient with hereditary multiple endocrine neoplasia 2B (MEN2B) syndrome with “highest risk” RET mutation Stem Cell Res. 2017 Aug;23:154-157. doi: 10.1016/j.scr.2017.07.022. Epub 2017 Jul 22. |
Human |
| 2017 |
Dermal fibroblasts |
Alonso-Barroso E, et al. (2017) Generation and characterization of a human iPSC line from a patient with propionic acidemia due to defects in the PCCA gene Stem Cell Res. 2017 Aug; 23:154-157 https://doi.org/10.1016/j.scr.2017.07.022. |
Human |
| 2017 |
Dermal fibroblasts |
Uhlen E, et al. (2017) Integration Free Derivation of Human Induced Pluripotent Stem Cells Using Laminin 521 Matrix J Vis Exp. 2017 Jul 7;(125). doi: 10.3791/56146. |
Human |
| 2017 |
Dermal fibroblasts |
Torriano S, et al. (2017) Pathogenicity of a novel missense variant associated with choroideremia and its impact on gene replacement therapy Hum Mol Genet. 2017 Sep 15;26(18):3573-3584. doi: 10.1093/hmg/ddx244. |
Human |
| 2017 |
Dermal fibroblasts |
Klein S, et al. (2017) A Marfan syndrome human induced pluripotent stem cell line with a heterozygous FBN1 c.4082G > A mutation, ISMMSi002-B, for disease modeling Stem Cell Res. 2017 Aug; 23:73-76 https://doi.org/10.1016/j.scr.2017.06.016. |
Human |
| 2017 |
Dermal fibroblasts |
Aguisanda F, et al. (2017) Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics Orphanet Journal of Rare Diseases 2017 Jun 28; 12(1):120. doi: 10.1186/s13023-017-0670-9. |
Human |
| 2017 |
Dermal fibroblasts |
Brookhauser N, et al. (2017) Long-Term Culture of Self-renewing Pancreatic Progenitors Derived from Human Pluripotent Stem Cells.Stem Cell Reports 2017 Jun 6;8(6):1675-1688. doi: 10.1016/j.stemcr.2017.05.019. |
Human |
| 2017 |
PBMCs |
Chen Y, et al. (2017) Generation of integration-free induced pluripotent stem cells (GZHMUi001-a) by reprogramming peripheral blood mononuclear cells from a 47, XXX syndrome patient. https://doi.org/10.1016/j.scr.2017.06.002. |
Human |
| 2017 |
PBMCs |
Brookhauser N, et al. (2017) Generation and characterization of human induced pluripotent stem cell (hiPSC) lines from an Alzheimer's disease (ASUi001-A) and non-demented control (ASUi002-A) patient homozygous for the Apolipoprotein e4 (APOE4) risk variant. https://doi.org/10.1016/j.scr.2017.06.003. |
Human |
| 2017 |
Stem cells from apical papilla (SCAP) and dental pulp stem cells (DPSC) |
Tan X, et al. (2017) Characterization of microRNAs expression profiles in human dental-derived pluripotent stem cells. PLoS One 2017 May 18;12(5):e0177832. doi: 10.1371/journal.pone.0177832. eCollection 2017. |
Human |
| 2017 |
Dermal fibroblasts |
Fields MA, et al. (2017) Extracellular matrix nitration alters growth factor release and activates bioactive complement in human retinal pigment epithelial cells. https://doi.org/10.1371/journal.pone.0177763. |
Human |
| 2017 |
Dermal fibroblasts |
Uusi-Rauva K, et al. (2017) Induced Pluripotent Stem Cells Derived from a CLN5 Patient Manifest Phenotypic Characteristics of Neuronal Ceroid Lipofuscinoses. Int J Mol Sci2017, 18, 955; doi:10.3390/ijms18050955. |
Human |
| 2017 |
Dermal fibroblasts |
Gabriel B, et al. (2017) Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders. J Vis Exp 2017 Apr 14;(122). doi: 10.3791/55372. |
Human |
| 2017 |
PBMCs |
Warren CR, et al. (2017) Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease. Cell Stem Cell 2017 Apr 6;20(4):547-557.e7. doi: 10.1016/j.stem.2017.01.010. |
Human |
| 2017 |
Dermal fibroblasts |
Tavian D, et al. (2017) Generation of induced pluripotent stem cells as disease modelling of NLSDM. Mol Genet Metab 2017 May;121(1):28-34. doi: 10.1016/j.ymgme.2017.03.009. Epub 2017 Apr 3. |
Human |
| 2017 |
Dermal fibroblasts |
Chen G, et al. (2017) Derivation of Human-Induced Pluripotent Stem Cells in Chemically Defined Medium. Methods Mol Biol2017;1590:131-137. doi: 10.1007/978-1-4939-6921-0_9. |
Human |
| 2017 |
Urinary cells |
Uhm KO, et al. (2017) Generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration system. Stem Cell Research 21 (2017) 44–46 https://doi.org/10.1016/j.scr.2017.03.019. |
Human |
| 2017 |
Cord blood CD34+ cells |
Haase A, et al. (2017) Generation of non-transgenic iPS cells from human cord blood CD34+ cells under animal component-free conditions. Stem Cell Research 21 (2017) 71–73 http://dx.doi.org/10.1016/j.scr.2017.03.022. |
Human |
| 2017 |
Dermal fibroblasts |
Buonocore F, et al. (2017) Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans. J Clin Invest 2017 May 1;127(5):1700-1713. doi: 10.1172/JCI91913. Epub 2017 Mar 27. |
Human |
| 2017 |
PBMCs |
Li Y, et al. (2017) Abnormal Neural Progenitor Cells Differentiated from Induced Pluripotent Stem Cells Partially Mimicked Development of TSC2 Neurological Abnormalities. Stem Cell Reports 2017 Apr 11;8(4):883-893. doi: 10.1016/j.stemcr.2017.02.020. Epub 2017 Mar 23. |
Human |
| 2017 |
PBMCs |
Varga E, et al. (2017) Establishment of an induced pluripotent stem cell (iPSC) line from a 9-year old male with autism spectrum disorder (ASD). Stem Cell Research 21 (2017) 16–18 http://dx.doi.org/10.1016/j.scr.2017.03.010. |
Human |
| 2017 |
Dermal fibroblasts |
Lukovic D, et al. (2017) Generation of a human iPSC line from a patient with retinitis pigmentosa caused by mutation in PRPF8 gene. Stem Cell Research 21 (2017) 23–25 http://dx.doi.org/10.1016/j.scr.2017.03.007. |
Human |
| 2017 |
Dermal fibroblasts |
Coppiello G, et al. (2017) Generation of Macaca fascicularis iPS cell line ATCi-MF1 from adult skin fibroblasts using non-integrative Sendai viruses. Stem Cell Research Volume 21, May 2017, Pages 1–4, https://doi.org/10.1016/j.scr.2017.03.008. |
Macaque |
| 2017 |
Primary conjunctival cells |
Geng Z, et al. (2017) Generation of retinal pigmented epithelium from iPSCs derived from the conjunctiva of donors with and without age related macular degeneration. PLoS One2017 Mar 10;12(3):e0173575. doi: 10.1371/journal.pone.0173575. eCollection 2017. |
Human |
| 2017 |
Fibroblasts |
Hunihan L, et al. (2017) Generation of a clonal induced pluripotent stem cell (iPSC) line expressing the mutant MECP2 allele from a Rett Syndrome patient fibroblast line. Stem Cell Research 2017 Apr;20:67-69. doi: 10.1016/j.scr.2017.02.017. Epub 2017 Mar 7. |
Human |
| 2017 |
Fibroblasts |
Jung-Klawitter S, et al. (2017) Generation of an iPSC line from a patient with GTP cyclohydrolase 1 (GCH1) deficiency: HDMC0061i-GCH1. Stem Cell Research 2017 Apr;20:38-41. doi: 10.1016/j.scr.2017.02.010. Epub 2017 Feb 24. |
Human |
| 2017 |
Fibroblasts |
Bharathan S, et al. (2017) Generation of an induced pluripotent stem cell line that mimics the disease phenotypes from a patient with Fanconi anemia by conditional complementation. Stem Cell Research 2017 Apr;20:54-57. doi: 10.1016/j.scr.2017.02.006. Epub 2017 Feb 22. |
Human |
| 2017 |
Dermal fibroblasts |
Trevisan M et al. (2017) Reprogramming Methods Do Not Affect Gene Expression Profile of Human Induced Pluripotent Stem Cells. Int J Mol Sci 18(1) 206 doi:10.3390/ijms18010206. |
Human |
| 2016 |
T lymphocytes |
Hashimoto A et al. (2016) Generation of induced pluripotent stem cells from patients With Duchenne muscular dystrophy and their Induction to cardiomyocytes. Int Heart J 57(1):112–7 doi:10.1536/ihj.15-376. Epub. |
Human |
| 2016 |
PBMCs |
Quintana-Bustamante O et al. (2016) Generation of patient-specific induced pluripotent stem cell from peripheral blood mononuclear cells by Sendai reprogramming vectors. Methods Mol Biol 2016;1353:1–11 doi:10.1007/7651_2014_170. |
Human |
| 2016 |
Fibroblasts |
Wiley LA et al. (2016) cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. Sci Rep. 6:30742 doi:10.1038/srep30742. |
Human |
| 2016 |
Urine epithelial cells |
Rossbach B et al. (2016) Generation of a human induced pluripotent stem cell line from urinary cells of a healthy donor using integration free Sendai technology. Stem Cell Research 16(2):314–7 doi:10.1016/j.scr.2015.12.018. Epub. |
Human |
| 2016 |
Fibroblasts, CD34+ cells |
Sivapatham R et al. (2016) Generation and characterization of patient-specific induced pluripotent stem cell for disease modeling. Methods in Molecular Biology 1353:25–44 doi: 10.1007/7651_2014_157. |
Human |
| 2015 |
Fibroblasts |
Beers J et al. (2015) A cost-effective and efficient reprogramming platform for large-scale production of integration-free human induced pluripotent stem cells in chemically defined culture. Sci Rep. 5:11319 doi:10.1038/srep11319. |
Human |
| 2015 |
Urine-derived cells |
Afzal MZ et al. (2015) Generation of Induced pluripotent stem cells from muscular dystrophy patients: efficient integration-free reprogramming of urine derived cells. J Vis Exp (95) e52032. doi:10.3791/52032. |
Human |
| 2015 |
BJ fibroblasts, adult dermal fibroblasts (HDF) |
Hribar KC et al. (2015) Nonlinear 3D projection printing of concave hydrogel microstructures for long-term multicellular spheroid and embryoid body culture. Lab Chip 15(11):2412–2418 doi:10.1039/c5lc00159e. |
Human |
| 2015 |
Adult cardiac fibroblast |
Zhang L et al. (2015) Derivation and high engraftment of patient-specific cardiomyocyte sheet using induced pluripotent stem cells generated from adult cardiac fibroblast. Circulation: Heart Failure 8:156–166 doi:10.1161/CIRCHEARTFAILURE.114a.001317. |
Human |
| 2015 |
PBMCs |
Soares FA et al. (2015) Generation of human induced pluripotent stem cells from peripheral blood mononuclear cells using Sendai virus. Methods Mol Biol. 1357:23–31 doi:10.1007/7651_2015_202. |
Human |
| 2015 |
Dermal fibroblasts |
Lahm H et al. (2015) Live fluorescent RNA-based detection of pluripotency gene expression in embryonic and induced pluripotent stem cells of different species. Stem Cells 33(2):392–402 doi: 10.1002/stem.1872. |
Human |
| 2015 |
Fibroblasts |
Rao RA et al. (2015) Ezh2 mediated H3K27me3 activity facilitates somatic transition during human pluripotent reprogramming. Sci Rep 5:8229 doi:10.1038/srep08229. |
Human |
| 2015 |
PBMCs |
Malchenko S et al. (2015) A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells. PLoS One 10(3):e0121707 doi:10.1371/journal.pone.0121707. |
Human |
| 2014 |
Peripheral mononuclear cells |
Fujie Y et al. (2014) New type of Sendai virus vector provides transgene-free iPS cells derived from chimpanzee blood. PLoS One 9(12):e113052 doi:10.1371/journal.pone.0113052. eCollection 2014. |
Human and chimpanzee |
| 2014 |
Human mammary epithelial cells (HMECs), primary fibroblasts |
Tokunaga K et al. (2014) Computational image analysis of colony and nuclear morphology to evaluate human induced pluripotent stem cells. Scientific Reports 4:6996 doi:10.1038/srep06996. |
Human |
| 2014 |
Primary fibroblasts |
Schlaeger TM et al. (2014) A comparison of non-integrating reprogramming methods. Nature Biotechnology 33:58–63. doi:10.1038/nbt.3070. |
Human |
| 2014 |
Amniotic fluid mesenchymal stromal cells (AF-MSCs) |
Jiang G et al (2014) Human transgene-free amniotic-fluid-derived induced pluripotent stem cells for autologous cell therapy. Stem Cells and Development 23(21):2613–2625 doi:10.1089/scd.2014.0110. |
Human |
| 2014 |
Finger-prick blood samples |
Tan HK et al. (2014) Human finger-prick induced pluripotent stem cells facilitate the development of stem cell banking. Stem Cells Trans Med 3:586–598 doi:10.5966/sctm.2013-0195. |
Human |
| 2014 |
Umbilical vein endothelial cells |
Nishio M et al. (2014) Differentiation of human pluripotent stem cells into highly functional classical brown adipocytes. Methods Enzymol 537:177–97 doi:10.1016/B978-0-12-411619-1.00010-0. |
Human |
| 2014 |
Adult fibroblasts |
Courtot AM et al. (2014) Morphological analysis of human induced pluripotent stem cells during induced differentiation and reverse programming. BioResearch Open Access 3(5):206–216 doi:10.1089/biores.2014.0028. |
Human |
| 2014 |
PBMCs |
Kishino Y et al. (2014) Derivation of transgene-free human induced pluripotent stem cells from human peripheral T cells in defined culture conditions. PLoS One 9(5):e97397 doi:10.1371/journal.pone.0097397. |
Human |
| 2014 |
Frozen non-cryoprotected dural and scalp fibroblasts |
Sproul AA et al. (2014) Generation of iPSC lines from archived non-cryoprotected biobanked dura mater. Acta Neuropathol Commun 2:4 doi:10.1186/2051–5960-2-4. |
Human |
| 2014 |
Dermal fibroblasts |
Chestkov IV et al. (2014) Patient-specific induced pluripotent stem cells for SOD1-associated amyotrophic lateral sclerosis pathogenesis studies. Acta Naturae 6(1) 54–60. |
Human |
| 2014 |
BJ fibroblasts |
Quintanilla RH Jr et al. (2014) CD44 Is a negative cell surface marker for pluripotent stem cell identification during human fibroblast reprogramming. PLoS ONE 9(1):e85419 doi:10.1371/journal.pone.0085419. |
Human |
| 2014 |
Peripheral blood T cells |
Takamatsu K et al. (2014). Degradation of amyloid beta by human induced pluripotent stem cell-derived macrophages expressing Neprilysin-2. Stem Cell Res 13(3 Pt A):442–53 doi:10.1016/j.scr.2014.10.001. |
Human |
| 2014 |
Fibroblasts |
Choi IY et al. (2014) Efficient generation human induced pluripotent stem cells from human somatic cells with Sendai-virus. J Vis Exp (86) e51406 doi:10.3791/51406. |
Human |
| 2014 |
Fibroblasts |
Burridge PW et al. (2014) Chemically defined generation of human cardiomyocytes. Nat Methods 11(8):855-60 doi:10.1038/nmeth.2999. |
Human |
| 2014 |
Dermal fibroblasts |
Nazor KL et al. (2014) Application of a low cost array-based technique - TAB-Array - for quantifying and mapping both 5mC and 5hmC at single base resolution in human pluripotent stem cells. Genomics 104(5):358–67 doi:10.1016/j.ygeno.2014.08.014. |
Human |
| 2014 |
Fibroblasts |
Woodard CM et al. (2014) iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson's disease. Cell Rep 9(4):1173–82 doi:10.1016/j.celrep.2014.10.023. |
Human |
| 2013 |
Dermal fibroblasts |
Shang L et al. (2013) ?-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome. Diabetes 63(3):923–933 doi:10.2337/db13-0717. |
Human |
| 2013 |
Fibroblasts |
Jianfeng Lu et al. (2013) Generation of integration-free and region-specific neural progenitors from primate fibroblasts. Cell Rep (5):1580–91 doi:10.1016/j.celrep.2013.04.004. Epub. |
Human and rhesus monkey |
| 2013 |
CD34+ |
Wang T et al. (2013) Derivation of neural stem cells from human adult peripheral CD34+ cells for an autologous model of neuroinflammation. PLoS One 8(11):e81720 doi:10.1371/journal.pone.0081720. |
Human |
| 2013 |
PBMC |
Chen IP et al. (2013) Induced pluripotent stem cell reprogramming by integration-free Sendai virus vectors from peripheral blood of patients with craniometaphyseal dysplasia. Cell Reprogram 15(6):503–13 doi:10.1089/cell.2013.0037. Epub. |
Human |
| 2013 |
PBMC |
Zhang XB (2013) Cellular reprogramming of human peripheral blood cells. Genomics Proteomics Bioinformatics 11(5):264–74 doi:10.1016/j.gpb.2013.09.001. Epub. |
Human |
| 2013 |
Multiple |
Bernal JA (2013) RNA based tools for nuclear reprogramming and lineage-conversion: Towards clinical applications. Cardiovasc Transl Res 6(6):956–68 doi:10.1007/s12265-013-9494-8. Epub. |
Human |
| 2013 |
CD34+ /PBMC |
Ye L et al. (2013) Blood cell-derived induced pluripotent stem cells free of reprogramming factors generated by Sendai virus vectors. Stem Cells Transl Med 2(8):558-66 doi:10.5966/sctm.2013–0006. Epub. |
Human |
| 2013 |
PBMC |
Churko JM et al. (2013) Generation of human iPSCs from human peripheral blood mononuclear cells unsing non-integrative Sendai virus in chemically defined conditions. Methods Mol Biol 1036:81–8 doi:10.1007/978-1-62703-511-8_7. |
Human |
| 2013 |
Fibroblasts |
Kahler DJ et al. (2013) Improved methods for reprogramming human dermal fibroblasts using fluorescence activated cell sorting. PLoS One 8(3):e59867 doi: 10.1371/journal.pone.0059867. Epub. |
Human |
| 2013 |
Blood or Fibroblasts |
Lieu PT et al. (2013) Generation of induced pluripotent stem cells with CytoTune, a non-integrating Sendai virus. Methods Mol Biol 997:45–56 doi:10.1007/978-1-62703-348-0_5. |
Human |
| 2013 |
Review article |
Malik N et al. (2013) A review of methods of human iPSC derivation. Methods Mol Biol 997:23–33 doi:10.1007/978-1-62703-348-0_3. Review. |
Human |
| 2013 |
Fibroblasts, keratinocytes and iris pigmented epithelial cells |
Tucker BA et al. (2013) Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. Stem Cells Transl Med 2(1):16–24 doi:10.5966/sctm.2012-0040. Epub. |
Human and Mouse |
| 2013 |
Fibroblasts |
Hua H et al. (2013) iPSC-derived β cells model diabetes due to glucokinase deficiency. J Clin Invest doi:10.1172/JCI67638 Epub ahead of print. |
Human |
| 2013 |
Fibroblasts |
Menendez L et al. (2013) Directed differentiation of human pluripotent cells to neural crest stem cells. Nat Protoc 8(1):203–12. Epub. |
Human |
| 2012 |
PBMC |
Yang W et al. (2012) iPSC reprogramming from human peripheral blood using Sendai virus mediated gene transfer. StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008–2012. |
Human |
| 2012 |
Blood |
Daheron L et al. (2012) Blood - SeV derived fibroblast generated iPSCs. StemBook [Internet] Cambridge (MA): Harvard Stem Cell Institute; 2008–2012. |
Human |
| 2012 |
CD34+ |
Nishishita N et al. (2012) Generation of virus-free induced pluripotent stem cell clones on a synthetic matrix via a single cell subcloning in the naïve state. PLoS One 2012;7(6):e38389 doi:10.1371/journal.pone.0038389. Epub. |
Human |
| 2012 |
Skeletal Myoblasts |
Trokovic R et al. (2012) Small molecule inhibitors promote efficient generation of induced pluripotent stem cells from human skeletal myoblasts. Stem Cells Dev 22(1):114–23. Epub. |
Human |
| 2012 |
Fibroblasts, cord blood cells and peripheral blood cells |
Kajiwara et al. (2012) Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells. Proc Natl Acad Sci USA 109(31):12538–43. Epub. |
Human |
| 2012 |
Cord blood CD34+ cells and fibroblasts |
Kumano et al. (2012) Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples. Blood 119(26):6234–42. Epub. |
Human |
| 2012 |
Nasal epithelial cells |
Ono M et al. (2012) Generation of induced pluripotent stem cells from human nasal epithelial cells using a Sendai virus vector. PLoS ONE 7(8):e42855 doi:10.1371/journal.pone.0042855. |
Human |
| 2012 |
Fibroblasts |
Kudva et al. (2012) Transgene-free disease-specific induced pluripotent stem cells from patients with Type 1 and Type 2 diabetes. Stem Cells Trans Med doi:10.5966/sctm.2011-0044. |
Human |
| 2012 |
Fibroblasts |
Jin et al. (2012) Integration-free induced pluripotent stem cells derived from retinitis pigmentosa patient for disease modeling. Stem Cells Trans Med doi:10.5966/sctm.2012-0005. |
Human |
| 2012 |
Fibroblasts |
Nakamura N et al. (2012) Feeder-free and serum-free production of hepatocytes, cholangiocytes, and their proliferating progenitors from human pluripotent stem cells: application to liver-specific functional and cytotoxic assays. Cell Reprogram 14(2):171–85. |
Human |
| 2012 |
Fibroblasts |
MacArthur C et al. (2012) Generation of human induced pluripotent stem cells by a nonintegrating RNA Sendai virus vector in feeder-free or xeno-free conditions. Stem Cells Int 2012:564612. |
Human |
| 2012 |
Peripheral blood |
Seki T et al. (2012) Generation of induced pluripotent stem cells from a small amount of human peripheral blood using a combination of activated T cells and Sendai virus. Nat Protoc 7(4):718–28. doi:10.1038/nprot.2012.015. |
Human |
| 2011 |
MRC-5 |
Kriks S et al. (2011) Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature doi:10.1038/nature10648. |
Human |
| 2011 |
Fibroblasts |
Yusa K et al. (2011) Targeted gene correction of _1-antitrypsin deficiency in induced pluripotent stem cells. Nature 478(7369):391–4 doi:10.1038/nature10424. |
Human |
| 2011 |
Peripheral circulating T cells |
Seki T et al. (2011) Derivation of induced pluripotent stem cells from human peripheral circulating T cells. Curr Protoc Stem Cell Biol Chapter 4:Unit4A.3. |
Human |
| 2011 |
Fibroblasts CD34+ cord blood cells |
Nishikawa S et al. (2011) Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. PNAS 108(34):14234–14239 doi:10.1073/pnas.1103509108. Epub. |
Human |
| 2010 |
Fibroblasts CD34+ cord blood cells |
Takayama N et al. (2010) Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells. J Exp Med 207(13):2817–30 doi:10.1084/jem.20100844. |
Human |
| 2010 |
T cells |
Seki T et al. (2010) Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells. Cell Stem Cell 7(1):11–14 doi:10.1016/j.stem.2010.06.003. |
Human |
| 2009 |
Fibroblasts |
Fusaki N et al. (2009) Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc Jpn Acad Ser B Phys Biol Sci 85(8):348–362. |
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