Select publications citing the Sendai virus vectors which are part of the CytoTune-iPS Sendai Reprogramming Kits.

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Year Reprogrammed cell type Reference Species
2017 BJ fibroblasts Trevisan M et al. (2017) Reprogramming Methods Do Not Affect Gene Expression Profile of Human Induced Pluripotent Stem Cells. Int J Mol Sci 18(1) 206 doi:10.3390/ijms18010206. Human
2016 T lymphocytes Hashimoto A et al. (2016) Generation of induced pluripotent stem cells from patients With Duchenne muscular dystrophy and their Induction to cardiomyocytes. Int Heart J 57(1):112–7 doi:10.1536/ihj.15-376. Epub. Human
2016 PBMCs Quintana-Bustamante O et al. (2016) Generation of patient-specific induced pluripotent stem cell from peripheral blood mononuclear cells by Sendai reprogramming vectors. Methods Mol Biol 2016;1353:1–11 doi:10.1007/7651_2014_170. Human
2016 Fibroblasts Wiley LA et al. (2016) cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. Sci Rep 6:30742 doi:10.1038/srep30742. Human
2016 Urine epithelial cells Rossbach B et al. (2016) Generation of a human induced pluripotent stem cell line from urinary cells of a healthy donor using integration free Sendai technology. Stem Cell Res 16(2):314–7 doi:10.1016/j.scr.2015.12.018. Epub. Human
2016 Fibroblasts, CD34+ cells Sivapatham R et al. (2016) Generation and characterization of patient-specific induced pluripotent stem cell for disease modeling. Methods in Molecular Biology 1353:25–44 doi: 10.1007/7651_2014_157. Human
2015 Fibroblasts Beers J et al. (2015) A cost-effective and efficient reprogramming platform for large-scale production of integration-free human induced pluripotent stem cells in chemically defined culture. Sci Rep 5:11319 doi:10.1038/srep11319. Human
2015 Urine-derived cells Afzal MZ et al. (2015) Generation of Induced pluripotent stem cells from muscular dystrophy patients: efficient integration-free reprogramming of urine derived cells. J Vis Exp (95) e52032. doi:10.3791/52032. Human
2015 BJ fibroblasts, adult dermal fibroblasts (HDF) Hribar KC et al. (2015) Nonlinear 3D projection printing of concave hydrogel microstructures for long-term multicellular spheroid and embryoid body culture. Lab Chip 15(11):2412–2418 doi:10.1039/c5lc00159e. Human
2015 Adult cardiac fibroblast Zhang L et al. (2015) Derivation and high engraftment of patient-specific cardiomyocyte sheet using induced pluripotent stem cells generated from adult cardiac fibroblast. Circulation: Heart Failure 8:156–166 doi:10.1161/CIRCHEARTFAILURE.114a.001317. Human
2015 PBMCs Soares FA et al. (2015) Generation of human induced pluripotent stem cells from peripheral blood mononuclear cells using Sendai virus. Methods Mol Biol 1357:23–31 doi:10.1007/7651_2015_202. Human
2015 Dermal fibroblasts Lahm H et al. (2015) Live fluorescent RNA-based detection of pluripotency gene expression in embryonic and induced pluripotent stem cells of different species. Stem Cells 33(2):392–402 doi: 10.1002/stem.1872. Human
2015 Fibroblasts Rao RA et al. (2015) Ezh2 mediated H3K27me3 activity facilitates somatic transition during human pluripotent reprogramming. Sci Rep 5:8229 doi:10.1038/srep08229. Human
2015 PBMCs Malchenko S et al. (2015) A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells. PLoS One 10(3):e0121707 doi:10.1371/journal.pone.0121707. Human
2014 Peripheral mononuclear cells Fujie Y et al. (2014) New type of Sendai virus vector provides transgene-free iPS cells derived from chimpanzee blood. PLoS One 9(12):e113052 doi:10.1371/journal.pone.0113052. eCollection 2014. Human and chimpanzee
2014 Human mammary epithelial cells (HMECs), primary fibroblasts Tokunaga K et al. (2014) Computational image analysis of colony and nuclear morphology to evaluate human induced pluripotent stem cells. Scientific Reports 4:6996 doi:10.1038/srep06996. Human
2014 Primary fibroblasts Schlaeger TM et al. (2014) A comparison of non-integrating reprogramming methods. Nature Biotechnology 33:58–63. doi:10.1038/nbt.3070. Human
2014 Amniotic fluid mesenchymal stromal cells (AF-MSCs) Jiang G et al (2014) Human transgene-free amniotic-fluid-derived induced pluripotent stem cells for autologous cell therapy. Stem Cells and Development  23(21):2613–2625 doi:10.1089/scd.2014.0110. Human
2014 Finger-prick blood samples Tan HK et al. (2014) Human finger-prick induced pluripotent stem cells facilitate the development of stem cell banking. Stem Cells Trans Med 3:586–598 doi:10.5966/sctm.2013-0195. Human
2014 Umbilical vein endothelial cells Nishio M et al. (2014) Differentiation of human pluripotent stem cells into highly functional classical brown adipocytes. Methods Enzymol 537:177–97 doi:10.1016/B978-0-12-411619-1.00010-0. Human
2014 Adult fibroblasts Courtot AM et al. (2014) Morphological analysis of human induced pluripotent stem cells during induced differentiation and reverse programming. BioResearch Open Access 3(5):206–216 doi:10.1089/biores.2014.0028. Human
2014 PBMCs Kishino Y et al. (2014) Derivation of transgene-free human induced pluripotent stem cells from human peripheral T cells in defined culture conditions. PLoS One. 9(5):e97397 doi:10.1371/journal.pone.0097397. Human
2014 Frozen non-cryoprotected dural and scalp fibroblasts Sproul AA et al. (2014) Generation of iPSC lines from archived non-cryoprotected biobanked dura mater. Acta Neuropathol Commun 2:4 doi:10.1186/2051–5960-2-4. Human
2014 Dermal fibroblasts Chestkov IV et al. (2014) Patient-specific induced pluripotent stem cells for SOD1-associated amyotrophic lateral sclerosis pathogenesis studies. Acta Naturae 6(1) 54–60. Human
2014 BJ fibroblasts Quintanilla RH Jr et al. (2014) CD44 Is a negative cell surface marker for pluripotent stem cell identification during human fibroblast reprogramming. PLoS ONE 9(1):e85419 doi:10.1371/journal.pone.0085419. Human
2014 Peripheral blood T cells Takamatsu K et al. (2014). Degradation of amyloid beta by human induced pluripotent stem cell-derived macrophages expressing Neprilysin-2. Stem Cell Res 13(3 Pt A):442–53 doi:10.1016/j.scr.2014.10.001. Human
2014 Fibroblasts Choi IY et al. (2014) Efficient generation human induced pluripotent stem cells from human somatic cells with Sendai-virus. J Vis Exp (86) e51406 doi:10.3791/51406. Human
2014 Fibroblasts Burridge PW et al. (2014) Chemically defined generation of human cardiomyocytes. Nat Methods 11(8):855-60 doi:10.1038/nmeth.2999. Human
2014 Dermal fibroblasts Nazor KL et al. (2014) Application of a low cost array-based technique - TAB-Array - for quantifying and mapping both 5mC and 5hmC at single base resolution in human pluripotent stem cells. Genomics 104(5):358–67 doi:10.1016/j.ygeno.2014.08.014. Human
2014 Fibroblasts Woodard CM et al. (2014) iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson's disease. Cell Rep 9(4):1173–82 doi:10.1016/j.celrep.2014.10.023. Human
2013 Dermal fibroblasts Shang L et al. (2013) ?-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome. Diabetes 63(3):923–933 doi:10.2337/db13-0717. Human
2013 Fibroblasts Jianfeng Lu et al. (2013) Generation of integration-free and region-specific neural progenitors from primate fibroblasts. Cell Rep (5):1580–91 doi:10.1016/j.celrep.2013.04.004. Epub. Human and rhesus monkey
2013 CD34+ Wang T et al. (2013) Derivation of neural stem cells from human adult peripheral CD34+ cells for an autologous model of neuroinflammation.  PLoS One 8(11):e81720 doi:10.1371/journal.pone.0081720. Human
2013 PBMC Chen IP et al. (2013) Induced pluripotent stem cell reprogramming by integration-free Sendai virus vectors from peripheral blood of patients with craniometaphyseal dysplasia. Cell Reprogram 15(6):503–13 doi:10.1089/cell.2013.0037. Epub. Human
2013 PBMC Zhang XB (2013) Cellular reprogramming of human peripheral blood cells. Genomics Proteomics Bioinformatics 11(5):264–74 doi:10.1016/j.gpb.2013.09.001. Epub. Human
2013 Multiple Bernal JA (2013) RNA based tools for nuclear reprogramming and lineage-conversion: Towards clinical applications. Cardiovasc Transl Res 6(6):956–68 doi:10.1007/s12265-013-9494-8. Epub. Human
2013 CD34+ /PBMC Ye L et al. (2013) Blood cell-derived induced pluripotent stem cells free of reprogramming factors generated by Sendai virus vectors. Stem Cells Transl Med 2(8):558-66 doi:10.5966/sctm.2013–0006. Epub. Human
2013 PBMC Churko JM et al. (2013) Generation of human iPSCs from human peripheral blood mononuclear cells unsing non-integrative Sendai virus in chemically defined conditionsMethods Mol Biol 1036:81–8 doi:10.1007/978-1-62703-511-8_7. Human
2013 Fibroblasts Kahler DJ et al. (2013) Improved methods for reprogramming human dermal fibroblasts using fluorescence activated cell sorting. PLoS One 8(3):e59867 doi: 10.1371/journal.pone.0059867. Epub. Human
2013 Blood or Fibroblasts Lieu PT et al. (2013) Generation of induced pluripotent stem cells with CytoTune, a non-integrating Sendai virus. Methods Mol Biol 997:45–56 doi:10.1007/978-1-62703-348-0_5. Human
2013 Review article Malik N et al. (2013) A review of methods of human iPSC derivation. Methods Mol Biol 997:23–33 doi:10.1007/978-1-62703-348-0_3. Review. Human
2013 Fibroblasts, keratinocytes and iris pigmented epithelial cells Tucker BA et al. (2013) Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. Stem Cells Transl Med 2(1):16–24 doi:10.5966/sctm.2012-0040. Epub. Human and Mouse
2013 Fibroblasts Hua H et al. (2013) iPSC-derived β cells model diabetes due to glucokinase deficiency.  J Clin Invest doi:10.1172/JCI67638 Epub ahead of print. Human
2013 Fibroblasts Menendez L et al. (2013) Directed differentiation of human pluripotent cells to neural crest stem cells. Nat Protoc 8(1):203–12. Epub. Human
2012 PBMC Yang W et al. (2012) iPSC reprogramming from human peripheral blood using Sendai virus mediated gene transfer. StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008–2012. Human
2012 Blood Daheron L et al. (2012) Blood - SeV derived fibroblast generated iPSCs. StemBook [Internet] Cambridge (MA): Harvard Stem Cell Institute; 2008–2012. Human
2012 CD34+ Nishishita N et al. (2012) Generation of virus-free induced pluripotent stem cell clones on a synthetic matrix via a single cell subcloning in the naïve statePLoS One 2012;7(6):e38389 doi:10.1371/journal.pone.0038389. Epub. Human
2012 Skeletal Myoblasts Trokovic R et al. (2012) Small molecule inhibitors promote efficient generation of induced pluripotent stem cells from human skeletal myoblasts.  Stem Cells Dev 22(1):114–23. Epub. Human
2012 Fibroblasts, cord blood cells and peripheral blood cells Kajiwara et al. (2012) Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells. Proc Natl Acad Sci U S A 109(31):12538–43. Epub. Human
2012 Cord blood CD34+ cells and fibroblasts Kumano et al. (2012) Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples. Blood 119(26):6234–42. Epub. Human
2012 Nasal epithelial cells Ono M et al. (2012) Generation of induced pluripotent stem cells from human nasal epithelial cells using a Sendai virus vector. PLoS ONE 7(8):e42855 doi:10.1371/journal.pone.0042855. Human
2012 Fibroblasts Kudva et al. (2012) Transgene-free disease-specific induced pluripotent stem cells from patients with Type 1 and Type 2 diabetes. Stem Cells Trans Med doi:10.5966/sctm.2011-0044. Human
2012 Fibroblasts Jin et al. (2012) Integration-free induced pluripotent stem cells derived from retinitis pigmentosa patient for disease modeling. Stem Cells Trans Med doi:10.5966/sctm.2012-0005. Human
2012 Fibroblasts Nakamura N et al. (2012) Feeder-free and serum-free production of hepatocytes, cholangiocytes, and their proliferating progenitors from human pluripotent stem cells: application to liver-specific functional and cytotoxic assays. Cell Reprogram 14(2):171–85. Human 
2012 Fibroblasts MacArthur C et al. (2012) Generation of human induced pluripotent stem cells by a nonintegrating RNA Sendai virus vector in feeder-free or xeno-free conditions. Stem Cells Int 2012:564612. Human
2012 Peripheral blood Seki T et al. (2012) Generation of induced pluripotent stem cells from a small amount of human peripheral blood using a combination of activated T cells and Sendai virus. Nat Protoc 7(4):718–28. doi:10.1038/nprot.2012.015. Human
2011 MRC-5 Kriks S et al. (2011) Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature doi:10.1038/nature10648. Human
2011 Fibroblasts Yusa K et al. (2011) Targeted gene correction of _1-antitrypsin deficiency in induced pluripotent stem cells. Nature 478(7369):391–4 doi:10.1038/nature10424. Human
2011 Peripheral circulating T cells Seki T et al. (2011) Derivation of induced pluripotent stem cells from human peripheral circulating T cells. Curr Protoc Stem Cell Biol Chapter 4:Unit4A.3. Human
2011 Fibroblasts
CD34+ cord blood cells
Nishikawa S et al. (2011) Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. PNAS 108(34):14234–14239 doi:10.1073/pnas.1103509108. Epub. Human
2010 Fibroblasts
CD34+ cord blood cells
Takayama N et al. (2010) Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells. J Exp Med 207(13):2817–30 doi:10.1084/jem.20100844. Human
2010 T cells Seki T et al. (2010) Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells. Cell Stem Cell 7(1):11–14 doi:10.1016/j.stem.2010.06.003. Human
2009 Fibroblasts Fusaki N et al. (2009) Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc Jpn Acad Ser B Phys Biol Sci 85(8):348–362.