Holotranscobalamin ELISA Kits

ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Holotranscobalamin can be quantified in various samples, including plasma, serum.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated.... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Holotranscobalamin can be quantified in various samples, including plasma, serum.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Holotranscobalamin can be quantified in various samples, including plasma, serum.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Holotranscobalamin can be quantified in various samples, including plasma, serum.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits are ready-to-use and quality tested for sensitivity, specificity, precision and lot-to-lot consistency.

Target Information

Holotranscobalamin (holoTC) is a complex of vitamin B12 and the protein transcobalamin, which is essential for transporting vitamin B12 into cells. It binds to the receptor CD320, facilitating the transport of vitamin B12 across cell membranes, where vitamin B12 functions as a coenzyme for critical enzymatic reactions. Transcobalamin, also known as transcobalamin II, is a beta-globulin protein synthesized by ileal enterocytes, endothelial cells, macrophages, and hepatocytes, which transports newly absorbed vitamin B12 from the intestines to the liver and other body organs via receptor-mediated endocytosis. Genetic polymorphisms in the transcobalamin gene (TCN2), such as TCN2 776C->G and TCN2 67A->G, can influence the levels of holotranscobalamin in the serum, thus impacting overall vitamin B12 status in individuals. The holoTC level is often used as a biomarker for assessing vitamin B12 deficiency, which is critical for diagnosing conditions related to inadequate vitamin B12 absorption or metabolism.

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Invitrogen

Human Holo TC ELISA Kit

Invitrogen

Human Holo TC ELISA Kit

Sensitivity 0.00489 pmol/mL

Assay Range 0.00781-0.5

Sample Volume

Plasma

50 µL

Serum

50 µL

Time To Result

2 hr 30 min

(1 hr 20 min hands-on)

Price

Cat # EEL231

96 Tests

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Holotranscobalamin ELISA Kits

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