Thermo Scientific™

EGS (ethylene glycol bis(succinimidyl succinate))

Catalog number: 21565
Thermo Scientific™

EGS (ethylene glycol bis(succinimidyl succinate))

Catalog number: 21565
Catalog Number
21565
Unit Size
1 g
Price (USD)
Price: 245.00
Online price: 232.65
Your price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
215651 g
Price: 245.00
Online price: 232.65
Your price:
-
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Thermo Scientific Pierce EGS is a crosslinker that contains amine-reactive NHS-ester ends around a 12-atom spacer arm, which can be cleaved by treatment with hydroxylamine at pH 8.5.

Features of the EGS crosslinker:

Reactive groups: NHS ester (both ends)
Reactive towards: amino groups (primary amines)
• Water-insoluble (dissolve first in DMF or DMSO); compare to Sulfo-EGS
• Membrane-permeable, allowing for intracellular crosslinking
• Crosslinks formed are reversible at pH 8.5 using hydroxylamine for 3 to 6 hours at 37°C
• Lactose dehydrogenase retained 60% of its activity after reversible crosslinking with EGS

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
EGS (ethylene glycol bis(succinimidyl succinate))
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Chemical Reactivity
Amine-Amine
Cleavable
By Hydroxylamine
Description
EGS
Molecular Weight (g/mol)
456.36
PEGylated
No
Spacer Arm Length
16.1 Å
Cell Permeability
Yes
Shipping Condition
Ambient
Product Line
Pierce™
Labeling Method
Chemical Labeling
Crosslinker Type
Homobifunctional
Reactive Moiety
NHS Ester
Spacer
Medium (10 to 30 Å)
Form
Powder
Quantity
1 g
Solubility
DMF, DMSO
Format
Standard
Water Soluble
No
Product Type
Crosslinker

Contents & Storage

Upon receipt store at 4°C.

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