Thermo Scientific Pierce SIAB is a mid-length (10.6 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.
Features of SIAB:
• Reactive groups:NHS ester and iodoacetyl • Reactive toward: amino and sulfhydryl groups • Non-cleavable • Water-insoluble (dissolve first in DMF or DMSO); compare to Sulfo-SIAB • Used to prepare stable enzyme-IgG conjugates • Forms conjugates with liposomes
Product References: Crosslinker Application Guide -- search for recent literature references for this product