This PI4K2B (PI4K2 beta) recombinant human protein (full length) was expressed in insect cells. PI4K2B lipid kinase is a member of the phosphatidylinositol 4-kinase family (PI4K) that phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate which are immediate precursor of several important signaling and scaffolding molecules. PI4K2B is primarily a cytosolic PI4K that is recruited to membranes where it stimulates phosphatidylinositol 4,5-bisphosphate syntheses. PI4K2B uses phosphatidylinositol as its primary substrate and has no activity on phosphatidylinositol monophosphates. PI4K2B is a restricted minor histocompatibility antigen in patients that had been successfully treated with donor lymphocyte infusions for relapsed chronic myeloid leukemia after allogeneic stem cell transplantation. PI4K2B (PI4K2 beta) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the Adapta™ assay • Available in multiple pack sizes for convenient use • Also available in our SelectScreen Kinase Profiling Service
For Research Use Only. Not for use in diagnostic procedures.
Full Length, Recombinant, Active
Contents & Storage
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.