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Brefeldin A (from Penicillium brefeldianum)

Catalog number: B7450

Molecular Probes™  Related applications: Cell Structure

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Description

The fungal metabolite brefeldin A (BFA) has multiple targets in cells and has proven valuable for dissecting the cellular processes, including vesicle formation and kinesin distribution, involved in exporting newly synthesized proteins. We are pleased to offer the natural brefeldin A isolated from Penicillium brefeldianum. Exposing cells to BFA causes a distortion in intracellular protein traffic from the ER to the Golgi apparatus and the eventual loss of Golgi apparatus morphology; removal of BFA completely reverses these effects. BFA also alters the morphology of endosomes and lysosomes.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Product Size: 5 mg
Reagent Type: Sphingolipids
Shipping Condition: Room Temperature

Contents & storage

Store in freezer (-5 to -30°C).

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Manuals & protocols

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