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Invitrogen
JLP Polyclonal Antibody
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Product Details
PA5-111525
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human JLP. Recombinant protein control fragment (Product #RP-107069).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NLSGGKTRDG GSVVGASVFY KDVAGLDTEG SKQRSASQSS LDKLDQELKE QQKELKNQEE LSSLVWICTS THSATKVL
Highest antigen sequence indentity to the following orthologs: Mouse - 94%, Rat - 91%.
Target Information
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-Jun N-terminal kinase protein-associated leucine-zipper protein; c-Jun NH2-terminal kinase-associated leucine zipper protein; C-Jun-amino-terminal kinase-interacting protein 4; Cancer/testis antigen 89; CT89; HLC-6; Human lung cancer oncogene 6 protein; JIP-4; JLP; JNK interacting protein; JNK-associated leucine-zipper protein; JNK/SAPK-associated protein; lung cancer oncogene 4; lung cancer oncogene 6; Max-binding protein; Mitogen-activated protein kinase 8-interacting protein 4; PHET; PIG6; proliferation-inducing gene 6; Proliferation-inducing protein 6; Protein highly expressed in testis; Sperm surface protein; Sperm-associated antigen 9; Sperm-specific protein; Sunday driver 1; unnamed protein product
Gene Aliases: CT89; HLC-6; HLC4; HLC6; HSS; JIP-4; JIP4; JLP; KIAA0516; MAPK8IP4; PHET; PIG6; SPAG9; SYD1
UniProt ID: (Human) O60271
Entrez Gene ID: (Human) 9043
MAPK cascade
vesicle-mediated transport
positive regulation of cell migration
lysosome localization
retrograde transport, endosome to Golgi
positive regulation of MAPK cascade
negative regulation of neuron differentiation
positive regulation of neuron differentiation
striated muscle cell differentiation
negative regulation of dendrite extension
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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