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Invitrogen
ELF2 Polyclonal Antibody
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Product Details
PA5-52247
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ELF2. Recombinant protein control fragment (Product #RP-100697).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MTSAVVDSGG TILELSSNGV ENQEESEKVS EYPAVIVEPV PSARLEQGYA AQVLVYDDET YMMQDVAEEQ EVETENVETV EASVHSSNAH CTDKTIEAAE ALLHMESPTC LRDSRSPEFI HAAMRPDVIT ETVVEVSTEE SEP
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 85%.
Target Information
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: E74-like factor 2; E74-like factor 2 (ets domain transcription factor); ELF2; ets domain transcription factor; ets family transcription factor ELF2A2; ets family transcription factor ELF2C; ETS-related transcription factor Elf-2; New ETS-related factor
Gene Aliases: 2610036A20Rik; A230104O07Rik; AW111824; BB183398; ELF2; EU32; NERF; NERF-1A; NERF-1a,b; NERF-1B; NERF-2
UniProt ID: (Human) Q15723, (Mouse) Q9JHC9
Entrez Gene ID: (Human) 1998, (Rat) 361944, (Mouse) 69257
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell differentiation
positive regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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