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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: HEDKEWKFAR AKLWLSYFDD KCTLPPPFNI IPSPKTICYM ISSLSKWICS HTSKGKVKRQ NSLKEWRNLK QKRDENYQKV MCCLVHRYLT SMRQKMQSTD QATVENLNEL RQDLSKFRNE IRDLLGFRTS KYA
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 98%.
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Interacts with ITPR3. Appears to be ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: capacitative calcium channel protein Trp1; transient receptor potential canonical 1; transient receptor potential; Ca2+ permeable ion channel; transient receptor protein 1; TRPC1
Gene Aliases: HTRP-1; TRP1
UniProt ID: (Human) P48995
Entrez Gene ID: (Human) 7220
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