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Invitrogen
DSPG3 Polyclonal Antibody
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Product Details
PA5-58297
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DSPG3. Recombinant protein control fragment (Product #RP-97643).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LRDNKIRQLP ELPTTLTFID ISNNRLGRKG IKQEAFKDMY DLHHLYLTDN NLDHIPLPLP ENLRALHLQN NNILEMHEDT FCNV
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
Target Information
The DSPG3 gene is not well-characterized and does not appear in standard genomic databases as a distinct gene or protein coding entity. It is possible that DSPG3 refers to a specific type of dermatan sulfate proteoglycan, given the acronym DSPG, which typically relates to proteoglycans involved in extracellular matrix structure and modulation. Proteoglycans like dermatan sulfate proteoglycans are pivotal in maintaining tissue resilience and regulating cell signaling pathways by interacting with growth factors and cytokines. They contribute to developmental processes and tissue repair mechanisms, playing roles in cellular adhesion, proliferation, and migration. In the context of skeletal and connective tissues, DSPGs influence matrix assembly and modulate biomechanical properties, impacting processes such as angiogenesis and fibrosis. Proteoglycans are known for their importance in disease states, including cancer and fibrosis, where altered expression or structure can affect cellular interactions and disease progression. Further research is needed to understand the specifics of DSPG3's functions and its implications in health and disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dermatan sulfate proteoglycan 3; DSPG3proteoglycan-lb; Epiphycan; epiphycan proteoglycan; PG-Lb; Proteoglycan-Lb; Small chondroitin/dermatan sulfate proteoglycan; unnamed protein product
Gene Aliases: DSPG3; EPYC; Pg-Lb; PGLB; SLRR3B
UniProt ID: (Human) Q99645
Entrez Gene ID: (Human) 1833
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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