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Invitrogen
P2X5 Polyclonal Antibody
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Product Details
PA5-66958
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human P2X5. Recombinant protein control fragment (Product #RP-107603).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TNLIVTPNQRQ NVCAENEGIP DGACSKDSDC HAGEAVTAGN GVKTGRCLRR ENLARGTCEI FAWCPLETSS RPEEPFLKE
Highest antigen sequence identity to the following orthologs - mouse 74%, rat 74%.
Target Information
The P2X5 gene encodes a protein that is a member of the purinergic receptor family, P2X receptors. These receptors are ligand-gated ion channels activated by extracellular ATP. The P2X5 protein is primarily involved in the regulation of skeletal muscle, immune response, and sensory neuron functions. Structurally, P2X5 features two transmembrane domains, a large extracellular loop, and intracellular N- and C-termini. P2X5 is known to form both homomeric and heteromeric channels, contributing to its functional diversity in various tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP receptor; ATP receptor subunit; ionotropic ATP receptor P2X5; lymphoid-restricted histocompatibility antigen-1; MGC47755; P2RX5; P2X purinoceptor 5; P2X5; Purinergic receptor; purinergic receptor P2X, ligand gated ion channel, 5; unnamed protein product
Gene Aliases: LRH-1; P2RX5; P2X5; P2X5FL; P2X5R
UniProt ID: (Human) Q93086
Entrez Gene ID: (Human) 5026
purinergic nucleotide receptor activity
transmembrane signaling receptor activity
extracellular ATP-gated cation channel activity
ion channel activity
voltage-gated ion channel activity
ATP binding
channel activity
ATP-gated ion channel activity
identical protein binding
ligand-gated monoatomic anion channel activity
ion transport
chloride transport
signal transduction
nervous system development
response to pH
response to zinc ion
positive regulation of calcium ion transport into cytosol
response to ATP
ion transmembrane transport
purinergic nucleotide receptor signaling pathway
osteoclast maturation
regulation of skeletal muscle tissue regeneration
positive regulation of calcium-mediated signaling
response to calcium ion
excitatory postsynaptic potential
calcium ion transmembrane transport
cation transmembrane transport
anion transmembrane transport
positive regulation of calcium ion import across plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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