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Highest antigen sequence indentity to the following orthologs: Mouse (74%), Rat (74%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66958. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The P2X5 gene encodes a protein that is a member of the purinergic receptor family, P2X receptors. These receptors are ligand-gated ion channels activated by extracellular ATP. The P2X5 protein is primarily involved in the regulation of skeletal muscle, immune response, and sensory neuron functions. Structurally, P2X5 features two transmembrane domains, a large extracellular loop, and intracellular N- and C-termini. P2X5 is known to form both homomeric and heteromeric channels, contributing to its functional diversity in various tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP receptor; ATP receptor subunit; ionotropic ATP receptor P2X5; lymphoid-restricted histocompatibility antigen-1; MGC47755; P2RX5; P2X purinoceptor 5; P2X5; Purinergic receptor; purinergic receptor P2X, ligand gated ion channel, 5; unnamed protein product
Gene Aliases: LRH-1; P2RX5; P2X5; P2X5FL; P2X5R
UniProt ID: (Human) Q93086
Entrez Gene ID: (Human) 5026
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