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Invitrogen
IMPDH2 Polyclonal Antibody
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FIGURE: 1 / 2
IMPDH2 Antibody (PA5-102742) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded IMPDH2 in mouse heart tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with IMPDH2 polyclonal antibody (Product # PA5-102742) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102742
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human IMPDH2(Accession P12268), corresponding to amino acid residues G148-N198.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total IMPDH2.
Target Information
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein; IMP (inosine 5'-monophosphate) dehydrogenase 2; IMP (inosine monophosphate) dehydrogenase 2; IMP dehydrogenase (EC 1.2.1.14); IMP dehydrogenase 2; IMP dehydrogenase II; IMP dehydrogenase type II; IMP oxireductase 2; IMPD 2; IMPDH 2; IMPDH II; inosine 5' phosphate dehydrogenase 2; inosine 5'-phosphate dehydrogenase 2; inosine 5-monophosphate dehydrogenase 2; inosine monophosphate dehydrogenase type II; inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205); inosine-5'-monophosphate dehydrogenase type II; unnamed protein product
Gene Aliases: IMPD; IMPD 2; IMPD2; IMPDH 2; IMPDH-II
UniProt ID: (Human) P12268, (Mouse) P24547, (Rat) E9PU28
Entrez Gene ID: (Human) 3615, (Mouse) 23918, (Rat) 301005
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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