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Gibco™

BMP2 Recombinant Human Protein

Catalog number:  PHC7145

Related applications:

Cell Analysis

| Cell Culture

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Description

Recombinant Human Bone Morphogenetic Protein 2 (BMP2)is a bioactive protein intended for use in cell culture applications. BMP2is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. BMP2 acts as a disulfide-linked homodimer and induces bone and cartilage formation.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Bone Morphogenetic Protein 2 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Bone Morphogenetic Protein 2 (BMP2)specific activity is determined by the dose dependent induction of alkaline phosphatase in mouse chondrogenic cell line ATDC5.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NM001200
Endotoxin Level: < 0.1 ng/µg
Indicator Cell: mouse chondrogenic cell line ATDC5
Mass: 25 µg
Product Line: Gibco®
Purity or Quality Grade: Carrier-Free
Reactivity: Human
Shipping Condition: Wet Ice
Specific Activity: 1.0 x 104 - 1.0 x103 units⁄mg
Expression System: E. coli
Form: Lyophilized
Protein Family: Growth Factors & Receptors
Protein Form: Recombinant, Ligand
Protein Subtype: BMPs (Bone Morphogenetic Proteins) & Related Factors
Research Category: Stem Cell Research, Bone Research
Species: Human
Validated Application: Cell Culture
Gene ID (Entrez): 548717
Molecular Weight: 26 kDa
Purification Method: Sequential Chromatography
Purity: 95 %
Quantity: 10μg
Gene Alias: BMP-2, BMP-2, MGC114605, xBMP-2, xbmp2
Cell Type: Stem Cells
Biological Activity: ED50 range = 0.1-1.0 mg⁄mL

Contents & storage

Store lyophilized human BMP-2 at 2 to 8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤ –20°C. Avoid repeated freeze⁄thaw cycles.