TGFB1 Recombinant Human Protein

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Description

Recombinant Human Transforming Growth Factor β 1 (TGFB1) is a bioactive protein intended for use in cell culture applications. TGFB1 is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB1 acts synergistically with TGF-α in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB1 activation and signaling may result in apoptosis.

High purity—no interference from other proteins or contaminants
High biological activity—more results with less protein
Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Transforming Growth Factor β 1 is one of more than 250 Gibco® recombinant proteins available from Life Technologies. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Transforming Growth Factor β 1 (TGFB1) specific activity is determined by measuring the TGFB1 dose-dependent inhibition of proliferation of mouse HT-2 cells stimulated with mouse IL-4.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Biological Activity: ED50 = ≤ 0.2 ng⁄mL
Endotoxin Level: < 0.1 ng/µg
Expression: Mammalian
Form: Lyophilized
Gene Aliases: TGF-β1
Mass: 10 µg
Molecular Weight: 25 kDa
Product Size: 10 µg
Protein Family: Growth Factors & Receptors
Protein Form: Ligand, Recombinant
Protein Length or Portion (a.a.): 112 aa (2 identical)
Protein Subtype: TGFs (Transforming Growth Factors)
Purification: Sequential Chromatography
Research Category: Bone Research, Cardiovascular Research, Differentiation, Immunology, Neurobiology, Oncology, Stem Cell Research
Species: Human
Validated Application: Cell Culture
Shipping Condition: Wet Ice

Contents & storage

Store this lyophilized preparation at 2-8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤–20°C. Avoid repeated freeze⁄thaw cycles.

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Manuals & protocols

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