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TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_004603.1
Molecular Weight
62.9 kDa
Quantity
100μg
Gene Alias
TGFBR1 (ALK5)
KinaseFamily
STKR Kinase Family
Protein Tag
GST Tag
Kinase Group
Ser⁄Thr Kinases: TKL Group
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Full Length
Form
Liquid
Protein Subtype
Serine/Threonine Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Signal Transduction
Contents & Storage
Kinase proteins are shipped on dry ice and should be stored at -80°C.