The amine-reactive quencher, QSY™ 21 succinimidyl ester has a broad and intense absorption (∼661 nm maxima) but no fluorescence making자세히 알아보기
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카탈로그 번호
수량
Q20132
5 mg
카탈로그 번호 Q20132
제품 가격(KRW)
488,000
온라인 행사
Ends: 31-Mar-2026
573,000
할인액 85,000 (15%)
Each
카트에 추가하기
수량:
5 mg
제품 가격(KRW)
488,000
온라인 행사
Ends: 31-Mar-2026
573,000
할인액 85,000 (15%)
Each
카트에 추가하기
The amine-reactive quencher, QSY™ 21 succinimidyl ester has a broad and intense absorption (∼661 nm maxima) but no fluorescence making it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications.
For Research Use Only. Not for use in diagnostic procedures.
사양
화학물질 반응성Amine
라벨 또는 염료QSY™ 21
제품 유형Succinimidyl Ester
수량5 mg
반응성 부분Active Ester, Succinimidyl Ester
배송 조건Wet Ice
라벨 유형Quencher Dyes
제품라인QSY
Unit SizeEach
구성 및 보관
Store in freezer (-5 to -30°C) and protect from light.
인용 및 참조 문헌 (6)
인용 및 참조 문헌
Abstract
Imaging tuberculosis with endogenous beta-lactamase reporter enzyme fluorescence in live mice.
Authors:Kong Y, Yao H, Ren H, Subbian S, Cirillo SL, Sacchettini JC, Rao J, Cirillo JD,
Journal:Proc Natl Acad Sci U S A
PubMed ID:20566877
'The slow growth rate and genetic intractability of tubercle bacilli has hindered progress toward understanding tuberculosis, one of the most frequent causes of death worldwide. We overcame this roadblock through development of near-infrared (NIR) fluorogenic substrates for beta-lactamase, an enzyme expressed by tubercle bacilli, but not by their eukaryotic hosts, ... More
An improved cell-penetrating, caspase-activatable, near-infrared fluorescent peptide for apoptosis imaging.
Authors:Maxwell D, Chang Q, Zhang X, Barnett EM, Piwnica-Worms D,
Journal:Bioconjug Chem
PubMed ID:19331388
'Apoptosis is required for normal cellular homeostasis, and deregulation of the apoptotic process is implicated in various diseases. Previously, we developed a cell-penetrating near-infrared fluorescence (NIRF) probe based on an activatable strategy to detect apoptosis-associated caspase activity in vivo. This probe consisted of a cell-penetrating Tat peptide conjugated to an ... More
Tumor-specific detection of an optically targeted antibody combined with a quencher-conjugated neutravidin
Authors:Ogawa M, Kosaka N, Choyke PL, Kobayashi H,
Journal:Bioconjug Chem
PubMed ID:19072537
In vivo molecular cancer imaging with monoclonal antibodies has great potential not only for cancer detection, but also for cancer characterization. However, the prolonged retention of intravenously injected antibody in the blood causes low target tumor-to-background ratio (TBR). Avidin has been used as a ... More
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes.
Authors:Blum G, von Degenfeld G, Merchant MJ, Blau HM, Bogyo M,
Journal:Nat Chem Biol
PubMed ID:17828252
We have generated a series of quenched near-infrared fluorescent activity-based probes (qNIRF-ABPs) that covalently target the papain-family cysteine proteases shown previously to be important in multiple stages of tumorigenesis. These 'smart' probes emit a fluorescent signal only after covalently modifying a specific protease target. After intravenous injection of NIRF-ABPs into ... More
Time-resolved Förster-resonance-energy-transfer DNA assay on an active CMOS microarray.
Authors:Schwartz DE, Gong P, Shepard KL,
Journal:Biosens Bioelectron
PubMed ID:18515059
We present an active oligonucleotide microarray platform for time-resolved Förster-resonance-energy-transfer (TR-FRET) assays. In these assays, immobilized probe is labeled with a donor fluorophore and analyte target is labeled with a fluorescence quencher. Changes in the fluorescence decay lifetime of the donor are measured to determine the extent of hybridization. In ... More