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Invitrogen
Human PABPC1b (aa 415-441) Control Fragment Recombinant Protein
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Product Details
RP-105419
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
QTQNRAAYYPPSQIAQLRPSPRWTAQG
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66900. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
PABPC1b encodes a poly(A) binding protein|The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs|The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay|The gene is part of a small gene family including three protein-coding genes and several pseudogenes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); carboxypeptidase A1 (pancreatic); casein kinase I alpha S-like; caspase 1, apoptosis-related cysteine peptidase; CKI-alpha; CKI-alpha-like; class IVb beta tubulin; clock regulator kinase; CSNK1A1; cysteine protease; DNA ADP-ribosyltransferase PARP1; down-regulated in lung cancer; epididymis secretory sperm binding protein; epididymis secretory sperm binding protein Li 77p; G protein beta1/gamma2 subunit-interacting factor 1; H3 histone family, member A; HIST1H3A; histone 1, H3a; histone cluster 1 H3 family member a; histone cluster 1, H3a; histone H3/a; IL-1 beta-converting enzyme; IL1B-convertase; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; microtubule protein; microtubule-associated protein tau; NAD(+) ADP-ribosyltransferase 1; neurofibrillary tangle protein; pabpc1; paired helical filament-tau; pancreatic carboxypeptidase A; PHF-tau; poly (ADP-ribose) polymerase family, member 1; poly A binding protein, cytoplasmic 1 b; poly(A) binding protein, cytoplasmic 2; poly(ADP-ribose) polymerase; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; poly[ADP-ribose] synthase 1; protein phosphatase 1, regulatory subunit 103; protein poly-ADP-ribosyltransferase PARP1; Tau-derived paired helical filament hexapeptide; tubulin beta-2 chain; tubulin beta-2C chain; tubulin, beta 2C; tubulin, beta, 2; unnamed protein product; zgc:77608
Gene Aliases: ADPRT; ADPRT 1; ADPRT1; ARTD1; Beta2; CK1; CK1a; CKIa; CPA; DDPAC; FTD1; FTDP-17; H3/A; H3FA; HEL-S-77p; HIST1H3A; HLCDGP1; ICE; IL1BC; LCAEOD; MAPTL; MSTD; MTBT1; MTBT2; P45; PAB1; PABP; PABP1; PABPC2; PABPL1; pADPRT-1; PARP; PARP-1; PARS; Poly-PARP; PPND; PPOL; PPP1R103; PRO2975; TAU; tau-40; Tau-PHF6; TUBB2; TUBB2C
UniProt ID: (Human) P29466, (Human) P15085, (Human) P48729, (Human) Q8N752, (Human) P68431, (Human) P10636, (Human) P11940, (Human) P09874, (Human) P68371
Entrez Gene ID: (Human) 834, (Human) 1357, (Human) 1452, (Human) 122011, (Human) 8350, (Human) 4137, (Human) 26986, (Human) 142, (Human) 10383
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