Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61182. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
GRTP1, also known as germ cell-specific gene 1-related protein, is a protein that is expressed in the testis and is involved in the regulation of spermatogenesis, the process of sperm cell development. It is a member of the GRP family of proteins, which are characterized by a conserved motif called the GRP domain. GRTP1 is thought to play a role in the differentiation of spermatogonia into spermatocytes and in the regulation of meiosis, the process of cell division that produces haploid cells. Mutations in the GRTP1 gene have been associated with male infertility. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Growth hormone-regulated TBC protein 1; RP11-391H12.7; TBC1 domain family member 6
Gene Aliases: GRTP1; TBC1D6
UniProt ID: (Human) Q5TC63
Entrez Gene ID: (Human) 79774
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