GRTP1 Proteins

Protein Information

GRTP1, also known as germ cell-specific gene 1-related protein, is a protein that is expressed in the testis and is involved in the regulation of spermatogenesis, the process of sperm cell development. It is a member of the GRP family of proteins, which are characterized by a conserved motif called the GRP domain. GRTP1 is thought to play a role in the differentiation of spermatogonia into spermatocytes and in the regulation of meiosis, the process of cell division that produces haploid cells. Mutations in the GRTP1 gene have been associated with male infertility. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment.

Synonyms

5430401C05Rik; C81211; GH regulated TBC protein 1; growth hormone regulated TBC protein 1; growth hormone-regulated TBC protein 1; Grtp1; LRRGT00052; RP11-391H12.7; TBC1 domain family member 6; Tbc1d6