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Search Thermo Fisher Scientific
Highest antigen sequence indentity to the following orthologs: Mouse (31%), Rat (31%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57647. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes the human homolog of mouse morc and like the mouse protein it is testis-specific. Mouse studies support a testis-specific function since only male knockout mice are infertile; infertility is the only apparent defect. These studies further support a role for this protein early in spermatogenesis, possibly by affecting entry into apoptosis because testis from knockout mice show greatly increased numbers of apoptotic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cancer/testis antigen 33; CT33; microrchidia, mouse, homolog of; MORC family CW-type zinc finger protein 1; MORC1
Gene Aliases: CT33; MORC; MORC1; ZCW6
UniProt ID: (Human) Q86VD1
Entrez Gene ID: (Human) 27136
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