Explore and order TaqMan Assays for genes involved in antibiotic resistance
Antibiotic resistance (ABR) research has become a key focus area in recent times as antibiotic resistance becomes a greater threat to global public health. Real-time PCR is a widely available technology that can be used to detect ABR genes.
Thermo Fisher Scientific has developed a growing set of TaqMan real-time PCR assays for the detection of ABR genes. You can order these assays in single tubes, or you can create your own panel. View the complete list of ABR TaqMan Assays below, and explore our flexible ordering formats at the bottom of this page.
The discovery and production of antibiotics in the first half of the 20th century dramatically reduced the impact of bacterial infections on human health. With frequent overuse of antibiotics over time, bacteria can change in a way that reduces the effectiveness of the agents that are designed to prevent infections. In farm animals, this can lead to antibiotic-resistance genes entering the food chain.
The process for development of resistant bacteria is as follows:
- Upon exposure to antibiotics, the majority of the bacteria sensitive to it will die, with a small portion surviving.
- The surviving antibiotic-resistant bacteria multiply through repeated exposure to antibiotics and gain a greater share of the overall microbial population.
- This resistance further spreads to sensitive human populations through horizontal gene transfer of antibiotic resistance genes.
Antibiotic resistance TaqMan Assays
| Target Gene Name | Description | Assay ID |
|---|---|---|
| APX1 | Control | At02233912_G1 |
| OXA-1 | β-lactamase (class D) | Ba04646133_s1 |
| FOX | AmpC β-lactamase (Class C) | Ba04646126_s1 |
| GES | Carbapenemase (Class A) | Ba04646151_s1 |
| KPC | Carbapenemase (Class A) | Ba04646152_s1 |
| IMP-1 | Carbapenemase (Class B) | Ba04646131_s1 |
| NDM-1 (C) | Carbapenemase (Class B) | Ba04931076_s1 |
| blaOXA-48 | Carbapenemase (Class D) | Ba04930816_s1 |
| PER-1 | Extended Spectrum β-lactamase (Class A) | Ba04646140_s1 |
| VEB | Extended Spectrum β-lactamase (Class A) | Ba04646153_s1 |
| CTX-M Group 1 | Extended-Spectrum-β-Lactamase | Ba04646149_s1 |
| CTX-M Group 2 | Extended-Spectrum-β-Lactamase | Ba04646142_s1 |
| CTX-M Group 8/25 | Extended-Spectrum-β-Lactamase | Ba04646154_s1 |
| CTX-M Group 9 | Extended-Spectrum-β-Lactamase | Ba04646127_s1 |
| ermB | Macrolide Resistance | Pa04230913_s1 |
| qnrA | Quinolone Resistance | Ba04646160_s1 |
| qnrS | Quinolone Resistance | Ba04646145_s1 |
| VIM | verona integron-encoded metallo-β-lactamase | Ba04646155_s1 |
Explore our flexible formats
Design your own flexible, customizable, 3,072-reaction real-time plate—pre-loaded for you to use.
Order individual TaqMan pathogen detection assays in single tubes.
For Research Use Only. Not for use in diagnostic procedures.
