Custom panels for the molecular detection of infectious disease pathogens

Whether you need custom real-time PCR panels for specialized studies, changes in seasonality, or targets not commonly available, our custom panels give you the capability to select content optimized to your specific testing use cases. Our custom solutions allow you to easily build your own infectious disease panel or select and customize from a wide variety of pre-designed assays, including infectious disease and antibiotic resistance assays, designed to increased accuracy, analytical sensitivity, and scalability. By building custom panels that meet your specific laboratory needs, you can optimize your workflow and throughput, reduce turn-around time, and gain a competitive edge by designing a unique panel not available elsewhere.

Wide selection—leverage our library of pre-designed assays or create your own

Scalable—our variety of real-time PCR assay formats enable you to run tens to hundreds of samples per day on a single instrument  

Easy—build your own custom panel or assay with our online tools or with the assistance of our technical sales team

Antibiotic resistance (ABR)—complete your custom panels to include ABR testing

Custom controls—easily order synthetic amplification controls to match your custom panel

Superior service and support—analytical validation services to accelerate the implementation of new tests


Custom panels for the molecular detection of infectious disease pathogens

Leverage the extensive Applied Biosystems library of pre-designed infectious disease and ABR assays to design your own panel.

Design your own custom panel for any infectious disease testing, including:

Respiratory tract infection (RTI)

Gastrointestinal infection

Urinary tract infection (UTI)

Wound infection

Vaginal microbiota

Nail infection

Sexually transmitted infection (STI)

Antibiotic resistance (ABR) assays


Scalable PCR-based solutions

Applied Biosystems QuantStudio Real-Time PCR Instruments are built to optimize productivity and meet your sample processing needs.  Based on your throughput requirements and instrument capabilities, custom panels are available in a variety of formats.

OpenArray Plates—ideal when you have a large volume of samples or assays, a single nanofluidic OpenArray Plate run on a QuantStudio 12K Flex Real-Time System is equivalent to running eight 384-well plates

TaqMan Array Cards—best format for lower sample volumes compared to OpenArray. This format can run 8 samples per card with easy sample loading, on the QuantStudio 7 Flex or 12K Flex Real-Time PCR Systems.

TaqMan Array Plates—mid-throughput, pre-spotted 96- and 384-well plates in multiple assay configurations for use on the QuantStudio 5, QuantStudio 7, or QuantStudio 12K Flex Real-Time PCR Systems

Single Tube Assays—flexible, day-to-day experimental set-up in your own configuration and/or plate. This format can be run on all QuantStudio Real-Time PCR Systems


Easy-to-build custom panels

We make it easy to select and build custom panels in your preferred format. The process is efficient and involves choosing your format; identifying your targets of interest; selecting from a library of pre-designed assays; and placing your order. 

build-custom-panel2

Use the search tool to start designing your own panel. If you have any questions, please reach out to our technical sales specialist team to assist in panel design options and pricing.

The following how-to videos will help you search for Applied Biosystems TaqMan ABR, Microbe Detection, and Microbe Assays.

How to search for Applied Biosystems TaqMan Antibiotic Resistance Assays

How to search for Applied Biosystems TaqMan Microbe Detection Assays

How to perform a batch search for Applied Biosystems TaqMan Microbe Assays


Antibiotic resistance (ABR) assays

Antimicrobial resistance is a growing threat to public health. One of the ways in which bacteria become resistant is through the acquisition of resistance genes. These resistance genes can be shared between species of bacteria, rapidly amplifying the spread and threat of these organisms.  

Improved accuracy of pathogen identification and associated analysis of antibiotic-resistance genes can both be efficiently achieved through real-time PCR from the same sample and panel.  Our TaqMan real-time PCR assays for the detection of ABR genes can be added to your panel or may be purchased as single tubes to help you address ABR pathogens.

Learn more about antibiotic resistance. Download our fact sheet ›

Our top 10 antibiotic resistance TaqMan assays

Product name

Class

Sub-class

Assay ID

PBP2a family beta-lactam-resistantpeptidoglycan transpeptidase MecA (mecA)

Beta-lactam

Methicillin

Ba04230908_s1

Carbapenem-hydrolyzing class A beta-lactamase KPC (blaKPC)

Beta-lactam

Carbapenem

Ba04646152_s1

23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) (erm(B))

Macrolide

Macrolide

Ba04230913_s1

23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(C)

Macrolide

Macrolide

Ba07319994_s1

Quinolone resistance pentapeptide repeatprotein QnrA2 (qnrA)

Quinolone

Quinolone

Ba04646160_s1

sulfonamide-resistant dihydropteroate synthase Sul1

Sulfonamide

Sulfonamide

Ba07319988_s1

D-alanine-(R)-lactate ligase VanB (vanB)

Glycopeptide

Vancomycin

Ba04646150_s1

D-alanine-(R)-lactate ligase VanA (vanA)

Glycopeptide

Vancomycin

Ba04646147_s1

Tetracycline resistance ribosomal protectionprotein Tet(M) (tet(M))

Tetracycline

Tetracycline

Ba04230915_s1

Class A beta-lactamase SHV (blaSHV)

Beta-lactam

Beta-lactam

Ba04646134_s1


Custom amplification controls

TaqMan Custom DNA Controls contain a linearized, multi-target plasmid pool used for microbial detection using TaqMan OpenArray Plates or TaqMan Array Cards. These controls can be included as a positive control for panel-specific amplification, and the high concentration (5 x 107 copies/µL) products can also be used to determine parameters necessary for analytical validation (e.g., limit of detection and Ct cut-off values). During real-time PCR, the control can be used as a stand-alone sample to verify assay performance and help with troubleshooting.

Cat. no.

Description

# of targets

Concentration (copies/µL)

Volume (µL)

List price

A50319

TaqMan Custom DNA Control

≤20

1 x 105

1,000

$1,560

A50375

TaqMan Custom DNA Control

21 to 30

1 x 105

1,000

$2,080

A50376

TaqMan Custom DNA Control

31 to 50

1 x 105

1,000

$3,120

A50377

TaqMan Custom DNA Control

>50

1 x 105

1,000

Quote only

A50378

TaqMan Custom DNA Control

≤20

5 x 107

50

$2,600

A50379

TaqMan Custom DNA Control

21 to 30

5 x 107

50

$3,120

A50380

TaqMan Custom DNA Control

31 to 50

5 x 107

50

$4,160

A50381

TaqMan Custom DNA Control

>50

5 x 107

50

Quote only


All TaqMan Custom DNA Control products should be stored at –15°C to –25°C. Please allow four weeks for your TaqMan Custom DNA Control product to be manufactured.

Our custom panel solutions can be ordered with the support of GeneArt Scientists who are ready to help you via email.  Simply download and complete our order intake form and submit to geneartsupport@thermofisher.com.


Services

Testing laboratories are under constant pressure to stay compliant with standards while expanding the number of molecular tests offered. When adopting a new testing method, we can assist in validating the workflow to facilitate a successful launch.

Our analytical validation (AV) consulting services can speed up the launch process by up to 75% and cut costs by up to half. Our expert team will consult with you to help develop and optimize your validation workflow, while providing data analysis support and template documentation to fully maximize your instrument and reagent investment.

Learn more ›

 

 

 

 

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