Designed to make next-generation sequencing (NGS) accessible to clinical laboratories with all levels of sequencing expertise, the Ion Torrent Genexus Dx Integrated Sequencer delivers an effortless user experience while enabling regulatory compliance.
Easy and efficient workflow
With a single touchpoint and ten-minutes of hands-on time, the Genexus Dx Integrated Sequencer starts with purified nucleic acid and automates all remaining steps of the targeted NGS workflow, including cDNA synthesis and library preparation, template preparation, sequencing, data analysis, and variant reporting. The result is an efficient workflow that is easily implemented in a variety of clinical lab settings.
Robust and flexible design
The Genexus Dx Integrated Sequencer features dual-mode software enabling use of the instrument for both diagnostic and research applications. You even have the option to multiplex up to 32 library reactions per run (in increments of four) to maximize throughput, or to analyze individual samples as they come in, to maximize turnaround time.
Engineered to enable NGS in clinical labs
The Genexus Dx Integrated Sequencer enhances your laboratory's productivity and innovation, whether you are running diagnostic tests or performing clinical research.
The Genexus Dx Integrated Sequencer is ready to help testing labs in the European Union (EU) and other countries deliver critical genomic information to patients and their healthcare team.
Intended Use: The Ion Torrent Genexus Dx Integrated Sequencer is an in vitro diagnostic (IVD) medical device intended to be used by trained personnel in a professional laboratory environment for automated, qualitative targeted sequencing of human DNA or RNA extracted from formalin-fixed, paraffin-embedded (FFPE) tumor tissue samples or plasma samples. The Ion Torrent Genexus Dx System consists of the Ion Torrent Genexus Dx Integrated Sequencer, and the Ion Torrent Genexus Dx Software.
The hands-off, automated workflow from nucleic acid to variant report begins with run planning using Genexus Dx Software. During run planning the user can select their desired sample(s) and assay(s) and use the setup wizard to create a run plan for the sequencer. During sequencer setup, which takes ten minutes of hands-on time, the onboard vision system verifies consumable installation in real-time using barcode and RFID detection, ensuring proper setup before the run begins. After the run is completed, the user can view a report for each sample, sample-level quality control metrics, and a list of reagents that were used.
Consumables for the Genexus Dx Integrated Sequencer are designed to reduce labor and errors. Ready-to-load kits, chips, and packs simplify NGS setup and process. A barcode system works with on-board cameras to prevent setup and experimental errors.
Genomic profiling in precision oncology is transforming patient care, but long waiting periods for biomarker results can delay treatment decisions. The Oncomine Dx Express Test, a CE-IVD solution, enables laboratories to deliver clinically relevant genomic profiles in as little as 24 hours, to aid clinicians in making timely therapy decisions.
Equipment shouldn’t slow you down. In addition to hands-on training at your lab, we offer on-site service plans, self-paced online courses, remote support options, and consulting services to help you get the most from your product.
Get more information on service plans, qualification services, and training specific to your region, at thermofisher.com/instrumentservices.
For In Vitro Diagnostic Use. Not available in all countries including the United States.