Single Quadrupole GC-MS

Unstoppable productivity and performance

Choose the Thermo Scientific ISQ 7000 single quadrupole GC-MS system for time-proven performance and productivity. This GC-MS system is ideal for high-throughput laboratories that want to achieve uninterrupted productivity.

Introducing the ISQ 7000 single quadrupole GC-MS system

Laboratories performing food, environmental, or forensic toxicology testing demand analytical systems that are unstoppable in every way.  That's the inspiration behind the ISQ 7000 GC-MS system.


The ISQ 7000 GC-MS system delivers femtogram-level sensitivity, so you consistently meet required detection limits as you run samples, whether you run in SIM mode or in Full Scan. Achieving low detection limits requires breaking noise-reduction boundaries. The ISQ 7000 GC-MS system does so with a unique ion path that neutrals cannot navigate.

Choose either the rugged Thermo Scientific ExtractaBrite ion source technology or the ultra-sensitive, ultra-robust Thermo Scientific Advanced Electron Ionization (AEI) source. Available in a dedicated system configuration, the AEI source provides highly efficient ionization and a tightly focused ion beam to drive down instrument detection limits and reduce time-consuming sample concentration steps.


Extended instrument uptime reduces turnaround time and overhead. Robust design ensures that your ISQ 7000 GC-MS system continues to produce the highest-quality results possible. Whether you select the ExtractaBrite or AEI ion source, you benefit from high matrix tolerance to minimize routine maintenance.

With NeverVent technology for the ExtractaBrite source, it's possible to isolate the mass spectrometer from the gas chromatograph, allowing source cleaning, column replacement or injector maintenance, without downtime for venting. This boosts instrument productivity to unprecedented levels, meaning your time can be spent on producing quality results.


The ISQ 7000 GC-MS system advances the user experience and learning with automated software for instrument tuning, method development, targeted quantification and untargeted screening workflows. The software also makes it easy to transition to the ISQ 7000 GC-MS system from other platforms.

AutoSIM and t-SIM automate method development and optimization for targeted selected-ion-monitoring (SIM) workflows. Retention Time Alignment (RTA) adds an easy way to maintain retention times for high-throughput work. Untargeted screening methods are likewise simplified. Mass spectral deconvolution unravels heavy co-elution by reconstructing clean mass spectra, ready for library searching, identification, and confirmation. For any workflow, SmartTune simplifies tuning procedure and, if required, notifies the user for any necessary corrective actions.


In an evolving world, it's important to be prepared for the future. The fully scalable ISQ 7000 GC-MS system provides a upgrade path from basic to advanced configurations, allowing you to add capability if you need it. With five performance and price levels, and field-upgrade options, you can invest in fit-for-purpose solutions at the right cost and still be capable to expand the analytical capability in the future.


Pressure to increase productivity and the growing list of compounds that laboratories must quantify and screen, necessitate workflow-driven software. Intuitive Thermo Scientific Chromeleon Chromatography Data System (CDS) software is available to streamline quantitative workflows. Download ready-to-use Thermo Scientific eWorkflows from the Thermo Scientific AppsLab Library to jump-start method development. For U.S. EPA-based environmental applications, the Environmental Analysis Extension Pack provides a set of GC-MS e-workflow and reporting templates.

Talk to an expert about the power of UNSTOPPABLE single quadrupole GC-MS

Provide your contact information and we will have one of our experts contact you to answer any questions you may have about the UNSTOPPABLE ISQ 7000 single quadrupole GC-MS system.

Contact us

During this free webinar, hear from two Thermo Fisher Scientific scientists about switching from helium to hydrogen carrier gas for GC-MS analysis of volatile and semi-volatile organic compounds using U.S. EPA Methods 524 and 525. They discuss key modifications to both the GC and MS setup in hardware and methodologies which are necessary for successful migration to hydrogen carrier gas.

CMD SchemaApp code