Prelude SPLC system

Use this video training library, a supplement to your formal training on the instruments, to get the most out of your Prelude SPLC System and Transcend UHPLC System by learning more about how the system operates and how to properly set it up and keep it running smoothly. Avoid time-consuming service calls and learn to troubleshoot your system quickly and easily.

Please note that the Prelude SPLC System has been discontinued and has been replaced by the optimized Transcend TLX UHPLC system. Service, spare parts, and consumables for the Prelude SPLC System are still available through the normal channels. Please contact your local representative to discuss your system requirements.


This video library is designed to help you learn more and get the most out of your LC systems. Watch the video for an overview of the available topics.


Training Videos

Good Practices for Your Thermo Scientific Prelude SPLC System

Click on each of the sections below for a video tutorial about associated components of your Prelude SPLC system.

Introduction to the Prelude SPLC Good Practices Training Videos

Get an overview of all the videos in this training series and learn what to expect from each one.

Good practices for setting up the Prelude SPLC autosampler

Learn about good practices for setting up the Prelude SPLC System autosampler, including instruction on how to ensure that each part of the autosampler is set up and configured to best suit your purposes.

Good practices for setting up the Prelude SPLC pumps

Learn about proper practices for setting up the pumps of the Prelude SPLC system, including ensuring that each pump is ready to be used as intended for your purposes. Includes setting up the pumps, preparing, selecting and priming fresh solvents, and running pump seal checks and other tests.

Good practices for setting up the Prelude SPLC column compartment

Learn good practices for setting up columns in the Prelude SPLC system, ensuring that each channel is properly delivering solvents to the column and that the columns themselves are working as intended.

Good practices for pairing the Prelude SPLC with a mass spectrometer

Learn about good practices for setting up and using a mass spectrometer attached to your Prelude SPLC system. Training includes instruction on inspecting the gas supplies and connections as well as cleaning and functional testing of the ion source.

Good practices for determining Prelude SPLC system suitability

The final chapter in the Prelude SPLC training series covers testing the performance of your Prelude SPLC system with a mass spectrometer to show that it is performing appropriately for running your application.

Good Practices for Your Thermo Scientific Transcend UHPLC System

Click on each of the sections below for a video tutorial about associated components of your Transcend UHPLC System.

Introduction to the Transcend UHPLC Good Practices Training Videos

Get an overview of all the videos in this training series and learn what to expect from each one.

Good practices for setting up the Transcend UHPLC autosampler

Learn about good practices for setting up the Transcend UHPLC system autosampler, including instruction on how to ensure that each part of the autosampler is set up and configured to best suit your purposes.

Good practices for setting up the Transcend UHPLC pumps

Learn about good practices for setting up the pumps for your Transcend UHPLC system, including inspection, preparation, priming, and functional testing of mobile phase solvents, tubing, and degassers.

Good practices for setting up the Transcend UHPLC valve interface module (VIM)

Learn about good practices for using columns in the Transcend UHPLC VIM, including inspection and functional testing of valves, tubing, connections, and columns.

Good practices for pairing the Transcend UHPLC with a mass spectrometer

Learn about good practices for setting up and using a mass spectrometer attached to your Transcend UHPLC system. Training includes instruction on inspecting the gas supplies and connections as well as cleaning and functional testing of the ion source.

Good practices for determining Transcend UHPLC system suitability

The final chapter in the Transcend UHPLC training series covers testing the performance of your Transcend UHPLC system with a mass spectrometer to show that it is performing appropriately for running your application.

Speak to a sales specialist

For additional help with your Prelude SPLC system or Transcend UHPLC system, please visit the Contact Us page, select Technical Support, and enter "Prelude SPLC" or "Transcend UHPLC" into the text box. Our service professionals look forward to helping you optimize your system performance.