FIR Antibodies

Antibodies that detect FIR can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target FIR in Human, Mouse and Rat samples. Our FIR polyclonal antibodies are developed in Rabbit. Find the FIR antibody... Antibodies that detect FIR can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target FIR in Human, Mouse and Rat samples. Our FIR polyclonal antibodies are developed in Rabbit. Find the FIR antibody that fits your needs. Choose from 1 of 6 FIR antibodies,... Antibodies that detect FIR can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target FIR in Human, Mouse and Rat samples. Our FIR polyclonal antibodies are developed in Rabbit. Find the FIR antibody that fits your needs. Choose from 1 of 6 FIR antibodies, which have been validated in experiments with 7 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop... Antibodies that detect FIR can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry and ELISA. These antibodies target FIR in Human, Mouse and Rat samples. Our FIR polyclonal antibodies are developed in Rabbit. Find the FIR antibody that fits your needs. Choose from 1 of 6 FIR antibodies, which have been validated in experiments with 7 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

FARP2 (FERM, RhoGEF and pleckstrin domain-containing protein 2), also known as PLEKHC3 or FERM domain including RhoGEF (FIR), is a 1,545 amino acid protein that contains one FERM domain, one DH domain and two PH domains. It exists as two alternatively spliced isoforms that are abundantly expressed in brain, lung, and testis as well as in embryonic hippocampal and cortical neurons. FARP2 functions as a Rho-guanine nucleotide exchange factor that activates RAC1 and is thought to regulate neurite remodeling of embryonic neurons. Sema3A binding to neuropilin-1 induces the dissociation of FARP2 from plexin-A1, thereby activating FARP2's Rac GEF activity which is critical for repulsion of outgrowing axons and suppression of neuronal adhesion. Downregulation of the FARP2 gene has been implicated in autism.

Synonyms

AI465173; BC009153; D030026M03Rik; Farp2; FERM domain including RhoGEF; FERM domain-including RhoGEF; FERM, ARH/RhoGEF and pleckstrin domain protein 2; FERM, ARHGEF and pleckstrin domain-containing protein 2; FERM, RhoGEF and pleckstrin domain protein 2; FERM, RhoGEF and pleckstrin domain-containing protein 2; FGD1-related Cdc42-GEF; Fir; FRG; Kiaa0793; mKIAA0793; PH domain-containing family C member 3; pleckstrin homology domain-containing family C member 3; PLEKHC3

FIR Antibodies

Target Information

Synonyms

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