HAP1 Antibodies

Antibodies that detect HAP1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target HAP1 in Human, Mouse and Rat samples. Our HAP1 polyclonal and monoclonal antibodies are... Antibodies that detect HAP1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target HAP1 in Human, Mouse and Rat samples. Our HAP1 polyclonal and monoclonal antibodies are developed in Rabbit, Goat and Mouse.... Antibodies that detect HAP1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target HAP1 in Human, Mouse and Rat samples. Our HAP1 polyclonal and monoclonal antibodies are developed in Rabbit, Goat and Mouse. Find the HAP1 antibody that fits your needs. Choose from 1 of 13 HAP1 antibodies, which have been validated in experiments with 14 publications and 28 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot... Antibodies that detect HAP1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Flow Cytometry. These antibodies target HAP1 in Human, Mouse and Rat samples. Our HAP1 polyclonal and monoclonal antibodies are developed in Rabbit, Goat and Mouse. Find the HAP1 antibody that fits your needs. Choose from 1 of 13 HAP1 antibodies, which have been validated in experiments with 14 publications and 28 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. HAP1 was initially identified through a two-hybrid library screening; the binding of HAP1 to huntingtin correlated with the expansion of the polyglutamine tract. HAP1 also interacts with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), suggesting that HAP1 may play a role in vesicular trafficking or organelle transport. HAP1 is also involved with the huntingtin-enhanced BDNF transport along the cellular microtubles. Attenuation of this process led to the loss of neurotrophic support and neuronal toxicity, which suggests that loss of this function might contribute to pathogenesis. Several alternatively spliced isoforms have been described for HAP1.

Synonyms

Hap1; HAP-1; HAP-1 antibody; HAP1-A; HAP1-B; HAP2; hHLP1; HIP5; HLP; HLP1; huntingtin associated protein 1; huntingtin-associated protein 1; huntingtin-associated protein 2; neuroan 1

HAP1 Antibodies

Target Information

Synonyms

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