Antibodies that detect ICAM-1 (CD54) can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry and Immunohistochemistry (Frozen). These antibodies target ICAM-1 (CD54) in Human, Mouse, Rat, Bovine and Non-human primate samples. Our ICAM-1 (CD54) monoclonal, polyclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Mouse, Rabbit, Rat and Armenian Hamster. These antibodies have been verified by Relative expression, Cell treatment, IP-MS and Knockdown to confirm specificity to ICAM-1 (CD54). Find the ICAM-1 (CD54) antibody that fits your needs. Choose from 1 of 98 ICAM-1 (CD54) antibodies, which have been validated in experiments with 404 publications and 342 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
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ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.
CD54; cell surface glycoprotein P3.58; ICAM-1; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; Major group rhinovirus receptor; MALA-2; MyD10; sCD54; soluble CD54
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