Anti-INSR Antibodies

INSR Antibodies

Antibodies that detect INSR can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target INSR in Human, Mouse, Rat, Non-human primate and Monkey samples. Our INSR polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell Treatment and Relative Expression to confirm specificity to INSR. Find the INSR antibody that fits your needs. Choose from 1 of 38 INSR antibodies, which have been validated in experiments with 38 publications and 85 images featured in our data ... View more Antibodies that detect INSR can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and Immunocytochemistry. These antibodies target INSR in Human, Mouse, Rat, Non-human primate and Monkey samples. Our INSR polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell Treatment and Relative Expression to confirm specificity to INSR. Find the INSR antibody that fits your needs. Choose from 1 of 38 INSR antibodies, which have been validated in experiments with 38 publications and 85 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

INSR (insulin receptor, IR) is a heterodimeric protein complex that has an intracellular beta subunit and an extracellular alpha subunit, which is disulfide- linked to a transmembrane segment. The insulin ligand binds to the IR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR. In humans, the INSR gene is located on chromosome 19. Defects in INSR are the cause of various insulin resistance syndromes and IGF-1R defects may also cause some forms of growth retardation.

Synonyms

4932439J01Rik; CD 220; CD220; CD220 antigen; CD220 beta; CD221; D630014A15Rik; HHF 5; HHF5; IGF-I receptor; INSR; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR 1; IR beta; IR1; IR-1; IR-A; IR-B

INSR Antibodies

Target Information

Synonyms

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