Anti-ST2 Antibodies | Invitrogen

ST2 Antibodies

Antibodies that detect ST2 can be used in several scientific applications, including ELISA, Flow Cytometry, Western Blot, Immunohistochemistry and Functional assay. These antibodies target ST2 in Human, Mouse, Rat, Zebrafish and Porcine samples. Our ST2 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rat, Rabbit and Goat. These antibodies have been verified by Relative expression, Cell treatment, Knockdown and Neutralization to confirm specificity to ST2. Find the ST2 antibody that fits your needs. Choose from 1 of 73 ST2 antibodies, which have been validated in experiments with 128 publications and 161 images featured ... View more Antibodies that detect ST2 can be used in several scientific applications, including ELISA, Flow Cytometry, Western Blot, Immunohistochemistry and Functional assay. These antibodies target ST2 in Human, Mouse, Rat, Zebrafish and Porcine samples. Our ST2 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rat, Rabbit and Goat. These antibodies have been verified by Relative expression, Cell treatment, Knockdown and Neutralization to confirm specificity to ST2. Find the ST2 antibody that fits your needs. Choose from 1 of 73 ST2 antibodies, which have been validated in experiments with 128 publications and 161 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

IL-33R, also known as ST2, is a receptor for IL-33. It is a member of the IL-1 receptor family of innate receptors. Its extracellular domain consists of 3 Ig-like domains that directly interact with its co-receptor IL-1RAcP, and the ligand alarmin, IL-33. IL-33 ligation results in the association of IL-33R complex with its adaptor proteins MyD88, IRAK1, IRAK4 and TRAF6, and activation of the NF-kB, and MAPK pathways. This, in turn, instigates the release of chemokines and cytokines such as IL-5, IL-6, IL-8, and IL-13. Two most common isoforms of IL-33R that result from alternative splicing are ST2L ¿ the membrane bound form, and ST2S ¿ the soluble form. The membrane bound form can be released from the cell surface by proteolytic cleavage. The soluble forms have been suggested to act as decoys dampening the IL-33 signaling. IL-33R is primarily expressed by mast cells, basophils, and eosinophils. In mouse, IL-33R expression has been shown on ILC2 and Th2 cells. IL-33R signaling has been implicated in the number of immune conditions, including allergies, arthritis, atherosclerosis and sepsis.

Synonyms

DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2

ST2 Antibodies

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