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This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.
1600023A02Rik; dJ461P17.6; EDDM4; epididymal protein 4; epididymal secretory protein 4; Epididymal secretory protein E4; epididymis-specific, whey-acidic protein type, four-disulfide core; HE4; Major epididymis-specific protein E4; MGC57529; putative protease inhibitor WAP5; RE4; WAP domain containing protein HE4-V4; WAP domain-containing protein HE4; WAP four-disulfide core domain 2; WAP four-disulfide core domain protein 2; WAP5; Wfdc2
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