MA3019A488 detects protein disulphide-isomerase (PDI) from human, rat, porcine and mouse tissues as well as hamster cells.
The MA3019A488 antigen is purified rat PDI.
Pdi1p is a yeast protein disulfide isomerase. It is a major endoplasmic reticulum protein with chaperone and co-chaperone activity, involved in retention of resident ER proteins. It also has a role in recognizing proteins targeted for ER-associated degradation (ERAD) and is a member of the protein disulfide isomerase family. Proteins in this family also can break disulfide bonds on substrate proteins.
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Protein Aliases: Cellular thyroid hormone-binding protein; collagen prolyl 4-hydroxylase beta; DSI; Endoplasmic reticulum resident protein 59; ER protein 59; ERBA2L; ERp59; GIT; glutathione-insulin transhydrogenase; P4Hbeta; p55; p58; Pancreas-specific protein disulfide isomerase; pancreatic protein disulfide isomerase; PDI; PDIA1; pdia2; PDIp; PDIR; PHDB; PO4DB; PO4HB; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide; PROHB; Prolyl 4-hydroxylase subunit beta; prolyl 4-hydroxylase, beta polypeptide; protein disulfide isomerase; protein disulfide isomerase (pancreas) like; Protein disulfide isomerase (Prolyl 4-hydroxylase, beta polypeptide); protein disulfide isomerase A2; protein disulfide isomerase associated 2; protein disulfide isomerase family A, member 1; protein disulfide isomerase family A, member 2; protein disulfide isomerase, pancreatic; protein disulfide isomerase-associated 1; protein disulfide isomerase-associated 2; protein disulfide isomerase/oxidoreductase; Protein disulfide-isomerase; Protein disulfide-isomerase A2; protocollagen hydroxylase; Rho GDP dissociation inhibitor gamma; testicular secretory protein Li 32; Thbp; thyroid hormone-binding protein p55
Gene Aliases: 1810041F13Rik; AI661267; CLCRP1; DSI; ERBA2L; ERp59; GIT; I79_002399; I79_007873; P4HB; P4Hbeta; p58; PDA2; PDI; PDIA1; PDIA2; PDIP; Pdipl; PDIR; PHDB; PO4DB; PO4HB; PROHB; Thbp