Whole Transcriptome Analysis Sample Prep for Next Generation Sequencing

Whole transcriptome analysis is of growing importance in understanding how altered expression of genetic variants contributes to complex diseases such as cancer, diabetes, and heart disease. Analysis of genome-wide differential RNA expression provides researchers with greater insights into biological pathways and molecular mechanisms that regulate cell fate, development, and disease progression.  With a dynamic range to detect subtle changes in expression level in a hypothesis neutral environment, next generation sequencing enables the understanding of biological response to stimuli or environmental changes.